Results 131 to 140 of about 5,818,471 (412)

A GPU-Computing Approach to Solar Stokes Profile Inversion

, 2012
We present a new computational approach to the inversion of solar photospheric Stokes polarization profiles, under the Milne-Eddington model, for vector magnetography.
Brian J. Harker, Darwin, Davis, Eydenberg, Gray, Harker, Hestroffer, Karr, Kenneth J. Mighell, Landi Degl'Innocenti, Levenberg, NVIDIA Corp., NVIDIA Corp., Pierce, Press, Rachkovsky, Rees, Rees, Sanchez Almeida, Socas-Navarro, Unno   +20 more
core   +1 more source

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

Molecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair, Philip König, Milena Mijović, Jessica Kalla, Anil Baskan, Loan Tran, Kristina Draganić, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo, Velina S. Atanasova, Lisa Wozelka‐Oltjan, Leonhard Müllauer, Michael Bergmann, Raheleh Sheibani‐Tezerji, Gerda Egger   +17 more
wiley   +1 more source

FEniCS–preCICE: Coupling FEniCS to other simulation software

SoftwareX, 2021
The new software FEniCS–preCICE is a middle software layer, sitting in between the existing finite-element library FEniCS and the coupling library preCICE.
Benjamin Rodenberg, Ishaan Desai, Richard Hertrich, Alexander Jaust, Benjamin Uekermann   +4 more
doaj  

Parallel and distributed Gröbner bases computation in JAS [PDF]

arXiv, 2010
This paper considers parallel Gr\"obner bases algorithms on distributed memory parallel computers with multi-core compute nodes. We summarize three different Gr\"obner bases implementations: shared memory parallel, pure distributed memory parallel and distributed memory combined with shared memory parallelism.
arxiv  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

preCICE v2: A sustainable and user-friendly coupling library [version 2; peer review: 2 approved]

Open Research Europe, 2022
preCICE is a free/open-source coupling library. It enables creating partitioned multi-physics simulations by gluing together separate software packages. This paper summarizes the development efforts in preCICE of the past five years.
Oguz Ziya Koseomur, Peter Vollmer, Kyle Davis, Gerasimos Chourdakis, Miriam Schulte, Benjamin Rodenberg, Benjamin Uekermann, Frédéric Simonis, Hans-Joachim Bungartz, Georg Abrams, Ishaan Desai, Lucia Cheung Yau, Richard Hertrich, Konrad Eder, Alexander Rusch, Florian Lindner, David Schneider, Dmytro Sashko, Dominik Volland, Amin Totounferoush   +19 more
doaj  

Parallel parametric linear programming solving, and application to polyhedral computations [PDF]

arXiv, 2019
Parametric linear programming is central in polyhedral computations and in certain control applications.We propose a task-based scheme for parallelizing it, with quasi-linear speedup over large problems.
arxiv  

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Medical Image Retrieval Based On the Parallelization of the Cluster Sampling Algorithm [PDF]

arXiv, 2017
In this paper we develop parallel cluster sampling algorithms and show that a multi-chain version is embarrassingly parallel and can be used efficiently for medical image retrieval among other applications.
arxiv  

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source