Results 31 to 40 of about 372,480 (297)

An excitatory GABA loop operating in vivo

open access: yesFrontiers in Cellular Neuroscience, 2015
While it has been proposed that the conventional inhibitory neurotransmitter GABA can be excitatory in the mammalian brain, much remains to be learned concerning the circumstances and the cellular mechanisms governing potential excitatory GABA action ...
Guadalupe eAstorga   +8 more
doaj   +1 more source

Modeling co-operative volume signaling in a plexus of nitric oxide synthase-expressing neurons [PDF]

open access: yes, 2005
In vertebrate and invertebrate brains, nitric oxide (NO) synthase (NOS) is frequently expressed in extensive meshworks (plexuses) of exceedingly fine fibers.
Husbands, Philip   +4 more
core   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Study the Effect of Carbon Fiber Volume Fraction and their Orientations on the Thermal Conductivity of the Polymer Composite Materials.

open access: yesAl-Khawarizmi Engineering Journal, 2008
The effect of fiber volume fraction of the carbon fiber on the thermal conductivity of the polymer composite material was studied. Different percentages of carbon fibers were used (5%, 10%, 15%, 20%, and 25%).
Mohammed Sellab Hamza
doaj   +2 more sources

Formation and structure of calcium carbonate thin films and nanofibers precipitated in the presence of poly(allylamine hydrochloride) and magnesium ions [PDF]

open access: yes, 2013
That the cationic polyelectrolyte poly(allylamine hydrochloride) (PAH) exerts a significant influence on CaCO₃ precipitation challenges the idea that only anionic additives have this effect. Here, we show that in common with anionic polyelectrolytes such
Cantaert, Bram   +6 more
core   +2 more sources

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Evaluation of representativeness of elasticity modulus and apparent density of D20 strength class of Brazilian standard in timber structures design

open access: yesActa Scientiarum: Technology
The Brazilian code ABNT NBR 7190-1 (2022) presents different strength classes for hardwood and displays representative values for apparent density, compressive strength parallel to the grain and modulus of elasticity in parallel direction of fibers to ...
Vinicius Borges de Moura Aquino   +5 more
doaj   +1 more source

Characterization of Natural Cellulosic Fiber Obtained from the Flower Heads of Milk Thistle (Silybum marianum) as a Potential Polymer Reinforcement Material

open access: yesJournal of Natural Fibers, 2023
Natural fibers are being investigated as alternatives to synthetic fibers in composite materials. In this paper, the physical, chemical, thermal, and morphological characteristics of fibers derived from milk thistle flower heads were characterized as ...
Kawthar Z. Alzarieni   +3 more
doaj   +1 more source

Optical fiber coupling method and apparatus [PDF]

open access: yes, 1985
Systems are described for coupling a pair of optical fibers to pass light between them, which enables a coupler to be easily made, and with simple equipment, while closely controlling the characteristics of the coupler.
Goss, W. C.   +2 more
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

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