Results 41 to 50 of about 48,711 (267)
Cloud computing services that provide computing resources to users through the Internet also provide computing resources in a virtual machine form based on virtualization techniques.
Jueun Jeon +2 more
doaj +1 more source
There is an overview of parallel program derivation according to a specific methodology based on APM-abstract parallel machines by means of which decisions about parallelism are done gradually and using an appropriate model and parallelism is expressed by using userdefined operations in a common framework.
Donnell, J. O', Rünger, G.
openaire +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
An Arc-Flow Model for the Makespan Minimization Problem on Identical Parallel Machines
In this paper, we consider the basic makespan minimization problem on identical parallel machines. The aim of this study is to solve, to optimality the hard instances of the literature. We present an integer linear program based on an innovative arc-flow
Mehdi Mrad, Nizar Souayah
doaj +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Special Issue: Robotics and Parallel Kinematic Machines
Parallel kinematic machines (PKMs) are a class of robots that have long been recognized for their higher stiffness and high payload-to-weight ratio and precision compared to their serial counterparts [...]
Swaminath Venkateswaran
doaj +1 more source
A Feasible Architecture for ARM-Based Microserver Systems Considering Energy Efficiency
In this paper, we propose the architecture of the ARM-based server system and physically build the ARM-based server cluster board (SCB). Based on a real implementation, the efficiency of the microserver is evaluated to verify the benefits of the proposed
Sendren Sheng-Dong Xu, Teng-Chang Chang
doaj +1 more source
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source

