Results 61 to 70 of about 48,711 (267)
From Parallel Virtual Machine to Virtual Parallel Machine: The Unibus System [PDF]
, 2008 Network-based concurrent computing frameworks have matured over two decades. However, in the realm of multi-domain geographically distributed computing, their true potential is yet to be realized. Popularly termed "grids", these metacomputing systems have yet to see widespread adoption and use, partly due to challenges resulting from heterogeneity ...
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Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Scientific ReportsThis paper addresses a hybrid processing system in automotive mold casting, which involves single processing machines and parallel batch processing machines.
Hanpeng Wang +3 more
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MathematicsThis study addresses the multi-period, multi-item, single-stage capacitated lot sizing problem (CLSP) in a parallel machine environment with machine eligibility constraints under a make-to-order production policy. A mixed-integer linear programming (MILP)
Felipe T. Muñoz, Juan Ulloa-Navarro
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Applied SciencesThe cloud manufacturing (CMfg) platform serves as a centralized hub for allocating and scheduling tasks to distributed resources. It features a concrete two-agent model that addresses real-world industrial needs: the first agent handles long-term ...
Xin Xin, Suxia Zhou, Jinsheng Gao
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The Distributed Assembly Parallel Machine Scheduling Problem with eligibility constraints.
International Journal of Production Management and Engineering, 2015 In this paper we jointly consider realistic scheduling extensions: First we study the distributed unrelated parallel machines problems by which there is a set of identical factories with parallel machines in a production stage.
Sara Hatami +2 more
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Versatile vector tools for efficient protein screening across multiple expression systems
FEBS Open Bio, EarlyView.A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu +5 more
wiley +1 more source
Advances in Mechanical Engineering, 2017 Static performance evaluation is one of the most important issues during the design stage of tripod parallel kinematic machines. Taken the 1T2R tripods as examples, this article proposes two improved static performance indices, namely, local dexterity ...
Jun Zhang, Hanliang Fang, Tengfei Tang
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