Results 51 to 60 of about 2,273,334 (347)

Optimal mapping of joint faults into healthy joint velocity space for fault-tolerant redundant manipulators [PDF]

, 2011
redundant ...
Abdi, Abdi, Abdi, Anthony A. Maciejewski, Hamid Abdi, Roberts, Roberts, Saeid Nahavandi, Wu, Yakov Frayman, Zhao, Zhao, Zhao   +12 more
core   +3 more sources

Kinematic Analysis of a 3-Axis Parallel Manipulator: The P3

Advances in Mechanical Engineering, 2013
This paper presents kinematic analysis of a 3-axis parallel manipulator, called P3. The P3 parallel manipulator is developed based on a 3-PRRU parallel mechanism, where P denotes prismatic pair, R revolute pair, and U universal joint.
Qiaohong Chen, Zhi Chen, Xinxue Chai, Qinchuan Li   +3 more
doaj   +1 more source

The Parallel Manipulation Argument [PDF]

Ethics, 2016
Matt King has recently argued that the manipulation argument against compatibilism does not succeed by employing a dilemma: either the argument infelicitously relies on incompatibilist sourcehood c...
openaire   +1 more source

Stiffness analysis of overconstrained parallel manipulators [PDF]

Mechanism and Machine Theory, 2009
The paper presents a new stiffness modeling method for overconstrained parallel manipulators with flexible links and compliant actuating joints. It is based on a multidimensional lumped-parameter model that replaces the link flexibility by localized 6-dof virtual springs that describe both translational/rotational compliance and the coupling between ...
Pashkevich, Anatol, Chablat, Damien, Wenger, Philippe   +2 more
openaire   +3 more sources

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Kinematics and Workspace Analysis and Numerical Simulation of the 3-PRRRR Parallel Manipulator

Jixie chuandong, 2017
The Working space is an important performance and design index in evaluating parallel manipulator.The 3-PRRRR parallel manipulator branched chain is simplified reasonably,by using the D-H method,the 3-PRRRR parallel manipulator inverse kinematic analysis
Shi Mengrui, Zhaoxinhua
doaj  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Efficiency Improvement of Measurement Pose Selection Techniques in Robot Calibration [PDF]

, 2013
The paper deals with the design of experiments for manipulator geometric and elastostatic calibration based on the test-pose approach. The main attention is paid to the efficiency improvement of numerical techniques employed in the selection of optimal ...
Caro, Stéphane, Furet, Benoît, Klimchik, Alexandr, Pashkevich, Anatol, Wu, Yier   +4 more
core   +4 more sources

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Modal Decoupled Dynamics-Velocity Feed-Forward Motion Control of Multi-DOF Robotic Spine Brace

IEEE Access, 2018
Based on the parallel robotic manipulator, this paper proposes a motion control strategy for the novel robotic spine brace for spinal rehabilitation exercises.
Xinjian Niu, Chifu Yang, Bowen Tian, Xiang Li, Junwei Han, Sunil K. Agrawal   +5 more
doaj   +1 more source