Results 101 to 110 of about 33,423 (302)
The role of lipid metabolism in neuronal senescence
FEBS Open Bio, EarlyView.Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
Dynamics of the Orthoglide parallel robot [PDF]
, 2009 Recursive matrix relations for kinematics and dynamics of the Orthoglide parallel robot having three concurrent prismatic actuators are established in this paper.
Chablat, Damien +2 more
core +2 more sources
Kinematics, workspace and singularity analysis of a multi-mode parallel robot
, 2017 A family of reconfigurable parallel robots can change motion modes by passing through constraint singularities by locking and releasing some passive joints of the robot.
Chablat, Damien +2 more
core +2 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Appropriate Design of Parallel Manipulators [PDF]
, 2008 Although parallel structures have found a niche market in many applications such as machine tools, telescope positioning or food packaging, they are not as successful as expected. The main reason of this relative lack of success is that the study and hardware of parallel structures have clearly not reached the same level of completeness than the one of
Merlet, Jean-Pierre, Daney, D.
openaire +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
ActuatorsSerial-parallel hybrid manipulators featuring remote actuation via parallelogram mechanisms are highly valued for their low inertia and high stiffness.
Zhisen Wang +6 more
doaj +1 more source
A General Numerical Method for Hyper-Redundant Manipulator Inverse Kinematics [PDF]
, 1993 Hyper-redundant robots have a very large or infinite degree of kinematic redundancy. A generalized resolved-rate technique for solving hyper-redundant manipulator inverse kinematics using a backbone curve is introduced.
Chirikjian, Gregory S.
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source