Results 41 to 50 of about 33,400 (300)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Accuracy Improvement for Stiffness Modeling of Parallel Manipulators [PDF]

open access: yes, 2009
The paper focuses on the accuracy improvement of stiffness models for parallel manipulators, which are employed in high-speed precision machining. It is based on the integrated methodology that combines analytical and numerical techniques and deals with ...
Chablat, Damien   +3 more
core   +4 more sources

A method for extending planar axis-symmetric parallel manipulators to spatial mechanisms

open access: yes, 2015
This paper investigates axis-symmetric parallel manipulators, composed of a central base column and an arm system able to rotate around this column. The arm system includes several actuated upper arms, each connected to a manipulated platform by one or ...
Brogårdh,T   +4 more
core   +1 more source

Stiffness modeling for perfect and non-perfect parallel manipulators under internal and external loadings [PDF]

open access: yes, 2014
International audienceThe paper presents an advanced stiffness modeling technique for perfect and non-perfect parallel manipulators under internal and external loadings.
Chablat, Damien   +2 more
core   +4 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Accuracy Analysis of Two Parallel Manipulators

open access: yesInternational Journal of Engineering and Management Sciences, 2019
The aim of the study is to analyse and visualize the accuracy of two parallel manipulators. The kinematics are calculated using vectors and the Newton method.
Sándor Hajdu, Dávid Bodnár
doaj   +1 more source

Uniqueness Domains in the Workspace of Parallel Manipulators [PDF]

open access: yes, 1997
International audienceThis work investigates new kinematic features of parallel manipulators. It is well known that parallel manipulators admit generally several direct kinematic solutions for a given set of input joint values.
Chablat, Damien, Wenger, Philippe
core   +1 more source

Sensitivity comparison of planar parallel manipulators [PDF]

open access: yesMechanism and Machine Theory, 2010
This paper deals with the sensitivity comparison of three Degree-of-Freedom planar parallel manipulators. First, a methodology is described to obtain the sensitivity coefficients of the pose of the moving platform of the manipulators to variations in their geometric parameters and actuated variables.
Binaud, Nicolas   +2 more
openaire   +2 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

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