Results 41 to 50 of about 809,085 (214)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
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Design and Optimization of a Novel Three-Dimensional Force Sensor with Parallel Structure
Sensors, 2018 To measure large external forces exerted on a loading platform, a novel three-dimensional force sensor is developed in this paper. The proposed sensor was designed with a parallel mechanism with three degrees of freedom. Kinematic analysis of this sensor
Guanyu Huang +3 more
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A Deformable Configuration Planning Framework for a Parallel Wheel-Legged Robot Equipped with Lidar
Sensors, 2020 The wheel-legged hybrid robot (WLHR) is capable of adapting height and wheelbase configuration to traverse obstacles or rolling in confined space. Compared with legged and wheeled machines, it can be applied for more challenging mobile robotic exercises ...
Fei Guo +3 more
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
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Machines, 2023 In this paper, a spatial parallel mechanism with five degrees of freedom is studied in order to provide a promising dynamic model for the control design.
Dingxu Guo +3 more
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
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Positioning Accuracy Analysis of the Parallel Mechanism Near Singular Positions
International Journal of Applied Mechanics and Engineering, 2015 This paper presents a method of numerical modelling of parallel mechanisms with clearances in their kinematic pairs taken into account. The pairs with clearances are modelled as shape connections based on constraints in the form of contact interactions ...
J. Bałchanowski
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FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
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Kinematics and Workspace Analysis of 4-SPRR-SPR 5-DOF Parallel Mechanism
Jixie chuandong, 2019 Taking a 2T3R 5-DOF 4-SPRR-SPR parallel mechanism with rotating axis as the moving platform as the research object, the degree of freedom of the 4-SPRR-SPR parallel mechanism is analyzed by the screw theory, the inverse kinematics equation of the ...
Guo Qiang Cui Guohua Zhang Fan Yu Haidong Cheng Zhenyi
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BiomimeticsThe human wrist affects the ability to efficiently perform many manipulation tasks. Despite this, most upper-limb prostheses are focused on the hand’s mobility, which makes users compensate for the lost wrist mobility with complex manipulation strategies
Raffaele Di Gregorio
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