Results 51 to 60 of about 764,086 (315)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
A Small Range Six-Axis Accelerometer Designed with High Sensitivity DCB Elastic Element
Sensors, 2016 This paper describes a small range six-axis accelerometer (the measurement range of the sensor is ±g) with high sensitivity DCB (Double Cantilever Beam) elastic element.
Zhibo Sun +3 more
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IEEE Access, 2021 Since the parallel mechanism has many advantages, such as high strength, high precision and so on, many industrial applications require mechanisms with three-dimensional translational and two-dimensional rotational motion (3T2R), 3T2R parallel mechanisms
Xuyu Hu, Hongzhao Liu
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Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
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Stiffness Analysis of a New Low Coupling 3T1R Asymmetrical Parallel Mechanism
Jixie chuandong, 2019 Parallel robot manipulator with the function of space three translations and one rotation (3T1R) is widely used in industry because of its advantages of large working space, easy to realize high speed and low cost. The stiffness performance of a new 3T1R
Xu Zhengxiao, Wu Guanglei, Shen Huiping
doaj
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Vibration Analysis of 2-PR(Pa)U- 2-PR(Pa)R New Parallel Mechanism [PDF]
International Journal of Advanced Design and Manufacturing Technology, 2018 Parallel kinematic machines, are closed loop structures which have more accuracy, stiffness and ability to withstand high loads. In this paper the vibration equations of the new parallel mechanism, that has higher stiffness because of parallelogram ...
Mehran Mahboubkhah +3 more
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Design of a 3-DOF Parallel Manipulator to Compensate for Disturbances in Facade Cleaning
IEEE Access, 2020 This paper proposes a three-degree-of-freedom manifold composed of three linear actuators. The proposed mechanism consists of a workspace suitable for facade cleaning and can compensate for the horizontal position from disturbances in a gondola-based ...
Garam Park +4 more
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Parallel moving mechanical systems
Independent Journal of Management & Production, 2014 Moving mechanical systems parallel structures are solid, fast, and accurate. Between parallel systems it is to be noticed Stewart platforms, as the oldest systems, fast, solid and precise. The work outlines a few main elements of Stewart platforms.
Petrescu, Florian Ion Tiberius +1 more
openaire +3 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source