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Paraneoplastic Pemphigus: Insight Into the Autoimmune Pathogenesis, Clinical Features and Therapy [PDF]
International Journal of Molecular Sciences, 2017 Paraneoplastic pemphigus is a rare autoimmune skin disease that is always associated with a neoplasm. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by paraneoplastic pemphigus patients.
Guido Granata +2 more
exaly +2 more sources
International Journal of Molecular Sciences, 2020 Skin manifestations of systemic disease and malignancy are extremely polymorphous. Clinicians should be familiarized with paraneoplastic dermatoses in order to perform an early diagnosis of the underlying neoplasm.
Giovanni Di Zenzo +2 more
exaly +2 more sources
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The Journal of Dermatology, 2007
ABSTRACTParaneoplastic pemphigus (PNP) is a life‐threatening autoimmune blistering skin disease. Clinically, it is characterized by severe mucosal erosions and various cutaneous lesions associated with lymphoproliferative neoplasmas. Suprabasal acantholysis and clefts with scattered necrotic keratinocytes are the unique histopathological features.
Xuejun, Zhu, Bingxin, Zhang
+6 more sources
ABSTRACTParaneoplastic pemphigus (PNP) is a life‐threatening autoimmune blistering skin disease. Clinically, it is characterized by severe mucosal erosions and various cutaneous lesions associated with lymphoproliferative neoplasmas. Suprabasal acantholysis and clefts with scattered necrotic keratinocytes are the unique histopathological features.
Xuejun, Zhu, Bingxin, Zhang
+6 more sources
Dermatologic Clinics, 1993
Paraneoplastic pemphigus is a newly recognized disease that occurs in some patients with lymphoproliferative neoplasms and occasionally, solid tumors. Patients present with an acute illness of the mucosa and skin that shares clinical and histologic features with erythema multiforme, toxic epidermal necrolysis, and pemphigus vulgaris.
D F, Mutasim, N J, Pelc, G J, Anhalt
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Paraneoplastic pemphigus is a newly recognized disease that occurs in some patients with lymphoproliferative neoplasms and occasionally, solid tumors. Patients present with an acute illness of the mucosa and skin that shares clinical and histologic features with erythema multiforme, toxic epidermal necrolysis, and pemphigus vulgaris.
D F, Mutasim, N J, Pelc, G J, Anhalt
+6 more sources
Advances in Anatomic Pathology, 1999
A RARE DISEASE: Paraneoplastic pemphigus is an rare autoimmune bullous skin disease recently recognized. About 50 cases have been reported since its first description in 1990.Clinical signs are polymorphous resembling the cutaneomucosal manifestations of pemphigus vulgar (skin and mucosa erosions, fragile interdermal bullae), pemphigoid (urticaria ...
V, Descamps, S, Belaich
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A RARE DISEASE: Paraneoplastic pemphigus is an rare autoimmune bullous skin disease recently recognized. About 50 cases have been reported since its first description in 1990.Clinical signs are polymorphous resembling the cutaneomucosal manifestations of pemphigus vulgar (skin and mucosa erosions, fragile interdermal bullae), pemphigoid (urticaria ...
V, Descamps, S, Belaich
openaire +3 more sources
Pemphigus Vulgaris and Paraneoplastic Pemphigus
Oral and Maxillofacial Surgery Clinics of North America, 2008The history, epidemiology, pathophysiology, clinical presentation, diagnostic work-up, histopathology, and treatment of PV and PNP have been presented. These life-threatening, autoimmune, mucocutaneous bullous conditions may be encountered first by oral health providers and, therefore, deserve keen understanding and attention by the oral and ...
Wendell A, Edgin +2 more
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Paraneoplastic pemphigus in a dog
Veterinary Dermatology, 1998This report presents a case of paraneoplastic pemphigus in a 7‐year‐old female Bouvier. The dog initially showed extensive oral ulcerations that exacerbated upon treatment with trimethoprim‐sulfadiazine. Subsequently, the dog developed vesiculobullous and ulcerative lesions on the ear margins, the nose, periocular, and at the nail beds. Due to complete
, Lemmens +4 more
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Pemphigus Vulgaris and Paraneoplastic Pemphigus
2016The disease pemphigus encompasses a group of related blistering conditions characterized by circulating antibodies against keratinocyte cell surface antigens important in mediating cell-to-cell adhesion (Becker and Gaspari, Dermatol Clin, 1993;11:429; Lever. J Am Acad Dermatol. 1979;1:2).
Jeff Kushner, Michael B. Morgan
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Paraneoplastic pemphigus: a subset of patients with pemphigus and neoplasia
Journal of Cutaneous Pathology, 1993We reviewed the clinical, histologic, and immunofluorescence features of 20 patients with pemphigus and neoplasia and compared them will a control group of 17 patients with pemphigus without neoplasia. Patients with neoplasia were divided according to clinical, histologic, and immunofluorescence findings into those with paraneoplastic pemphigus ...
D R, Mehregan +5 more
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Paraneoplastic pemphigus/paraneoplastic autoimmune multiorgan syndrome
International Journal of Dermatology, 2009AbstractParaneoplastic pemphigus is the term used for an exclusive subset of pemphigus. The clinical lesions may resemble pemphigus, pemphigoid, erythema multiforme, graft‐vs.‐host disease, or lichen planus. A common denominator in all patients is the concomitant occurrence of either occult or confirmed systemic neoplasm.
Virendra N, Sehgal, Govind, Srivastava
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