Results 61 to 70 of about 2,340 (187)
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Romeo Patini +9 more
wiley +1 more source
Association Between Oral Lichen Planus and Non‐Oral Cancers: A Multicentre Case–Control SIPMO Study
ABSTRACT Objectives This multicentre case–control study aimed to investigate the potential association between oral lichen planus (OLP) and extraoral cancers. The secondary objective included the identification of risk factors for this association. Methods The study was conducted between January 2023 and June 2024 and included 21 Italian Oral Medicine ...
Gioele Gioco +62 more
wiley +1 more source
Immunofluorescence testing in the diagnosis of autoimmune blistering diseases: overview of 10-year experience [PDF]
BACKGROUND: Immunofluorescence testing is an important tool for diagnosing blistering diseases. OBJECTIVE: To characterize the immunofluorescence findings in patients diagnosed with autoimmune blistering skin diseases.
Samia Trigo Arbache +4 more
doaj +1 more source
Navigating the Complexities of Pemphigus Vulgaris: A Comprehensive Iranian Study
We conducted a cross‐sectional analysis of 63 patients diagnosed with pemphigus vulgaris, confirmed by biopsy. Information was collected via telephone interviews. The research aimed to assess the demographic characteristics, initial symptoms, diagnosis delays, and treatment outcomes of the participants.
Delaram Moosavi +7 more
wiley +1 more source
Snapshot Look at Castleman Disease
ABSTRACT Castleman disease (CD) is a rare and heterogeneous group of lymphoproliferative disorders characterised by abnormal proliferation of lymphoid tissue. First described in the 1950s, it has since been classified into two major clinical forms: unicentric CD (UCD), involving a single lymph node region and multicentric CD (MCD), which affects ...
Ciprian Jitaru +17 more
wiley +1 more source
Background/Objectives: Pemphigus is a rare blistering disease characterized by a chronic course, associated with significant mortality and morbidity. This review article aims to delve into three Pemphigus subtypes: Pemphigus Vulgaris, Pemphigus Foliaceus
Pokphazz Christjaroon +2 more
doaj +1 more source
Expert Perspective: Diagnosis and Treatment of Castleman Disease
Castleman disease (CD) is a major diagnostic challenge for rheumatologists. Unicentric CD (UCD) involves one enlarged lymph node region, whereas multicentric CD (MCD) involves multiple enlarged lymph node regions. Both UCD and MCD may exhibit a wide range of symptoms that overlap with other immune‐mediated conditions.
Luke Y. C. Chen +2 more
wiley +1 more source
Recent Progress in Double Filtration Plasmapheresis
ABSTRACT Double‐filtration plasmapheresis is an advanced extracorporeal blood purification technique that selectively removes pathogenic macromolecules based on molecular weight. Unlike conventional plasma exchange, double‐filtration plasmapheresis uses a two‐step filtration process to retain beneficial plasma components such as albumin, while ...
Dan Li +3 more
wiley +1 more source
Pemphigus vulgaris as the first manifestation of multiple myeloma: a case report
Background The association between pemphigus and malignancy has been well documented for decades but an association between pemphigus vulgaris and multiple myeloma is unusual. We report a case of pemphigus vulgaris revealing multiple myeloma.
Fandresena Arilala Sendrasoa +7 more
doaj +1 more source
AIRE's Complex Role Beyond Promiscuous Gene Expression
ABSTRACT Central tolerance, established in the thymus, ensures T cells are nonreactive to self‐antigens while maintaining a functional immune repertoire. Medullary thymic epithelial cells (mTECs) and thymic dendritic cells (DCs) play a crucial role in this mechanism by orchestrating the selection and deletion of autoreactive thymocytes, a process ...
Pärt Peterson
wiley +1 more source

