Results 61 to 70 of about 18,804 (147)

Bispecific Dual‐Immune Checkpoint Inhibitor Associated Cutaneous Toxicity: A Report of Lorigerlimab Adverse Skin Reaction in Two Cancer Patients

Journal of Cutaneous Pathology, Volume 53, Issue 5, Page 422-426, May 2026.
ABSTRACT Lorigerlimab is a dual bispecific antibody (BsAb) targeting cytotoxic T‐lymphocyte‐associated protein 4 and programmed cell death protein 1 that is used for treatment of advanced solid cancers such as metastatic castration‐resistant prostate carcinoma.
Niloofar Sina, Fiorinda Muhaj, Volha Lenskaya, Doina Ivan, Victor G. Prieto, Jonathan L. Curry   +5 more
wiley   +1 more source

Oral manifestation of paraneoplastic pemphigus [PDF]

, 2019
Paraneoplastic pemphigus (PNP) is a rare and often fatal autoimmune blistering disease accompanied by both benign and malignant neoplasms. Usually, oral, skin, and mucosal lesions are the earliest manifestations shown by PNP patients.
박연정, 최종훈, 권정승, 안형준   +3 more
core   +1 more source

Paraneoplastic pemphigus: Diagnostic mimics, confounders and management challenges in a series of five long‐term survivors from a single centre

Skin Health and Disease, 2023
We present a series of five cases who presented to our institution with treatment‐refractory mucosal ulceration, all of whom were subsequently diagnosed with paraneoplastic pemphigus (PNP).
Jonathan S. Emerson, Mark Schifter, Pei Dai, Jocelyn Jiang, Mark S. Taylor, Michelle Kang, Kenelm Kwong, Hadleigh Clark, Suzanne Cullican, David Campbell, Ming‐Wei Lin   +10 more
doaj   +1 more source

Diagnostic Agreement in Subepidermal Blistering Diseases: Is ELISA Test Reliable as Direct Immunofluorescence? A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

Journal of Oral Pathology &Medicine, Volume 55, Issue 4, Page 391-418, April 2026.
ABSTRACT Objectives Direct immunofluorescence (DIF) is the gold standard for diagnosing subepidermal blistering diseases (SBDs). However, DIF requires specialized expertise; therefore, alternative immunological methods such as enzyme‐linked immunosorbent assays (ELISA) are worth exploring. The aim of this review was to evaluate the diagnostic agreement
Romeo Patini, Gioele Gioco, Michele Davide Mignogna, Stefania Leuci, Francesco Scilla, Davide Gentile, Cosimo Rupe, Enrico Russo, Anna Schiavelli, Carlo Lajolo   +9 more
wiley   +1 more source

Safety and Efficacy of Pemphigus Treatments: A Subtype-Specific Review of Conventional and Emerging Therapies

BioChem
Background/Objectives: Pemphigus is a rare blistering disease characterized by a chronic course, associated with significant mortality and morbidity. This review article aims to delve into three Pemphigus subtypes: Pemphigus Vulgaris, Pemphigus Foliaceus
Pokphazz Christjaroon, Orli Wagon, Artiene H. Tatian   +2 more
doaj   +1 more source

Immunofluorescence testing in the diagnosis of autoimmune blistering diseases: overview of 10-year experience [PDF]

Anais Brasileiros de Dermatologia, 2014
BACKGROUND: Immunofluorescence testing is an important tool for diagnosing blistering diseases. OBJECTIVE: To characterize the immunofluorescence findings in patients diagnosed with autoimmune blistering skin diseases.
Samia Trigo Arbache, Tarsila Gasparotto Nogueira, Lívia Delgado, Denise Miyamoto, Valéria Aoki   +4 more
doaj   +1 more source

Association Between Oral Lichen Planus and Non‐Oral Cancers: A Multicentre Case–Control SIPMO Study

Oral Diseases, Volume 32, Issue 4, Page 1054-1067, April 2026.
ABSTRACT Objectives This multicentre case–control study aimed to investigate the potential association between oral lichen planus (OLP) and extraoral cancers. The secondary objective included the identification of risk factors for this association. Methods The study was conducted between January 2023 and June 2024 and included 21 Italian Oral Medicine ...
Gioele Gioco, Anna Schiavelli, Alessandra Majorana, Elena Bardellini, Silvio Abati, Andrea Sardella, Francesco Spadari, Matteo Pellegrini, Dorina Lauritano, Raffaele Borgia, Monica Pentenero, Samuele Sutera, Paolo Giacomo Arduino, Alessio Gambino, Roberto Broccoletti, Matteo Biasotto, Giulia Ottaviani, Lorenzo Azzi, Alessandro D'Aiuto, Davide Bartolomeo Gissi, Andrea Gabusi, Andrea Santarelli, Marco Mascitti, Paolo Vescovi, Gloria Bortolotti, Maddalena Manfredi, Marco Meleti, Grazia Zino, Umberto Romeo, Gianluca Tenore, Gianfranco Favia, Luisa Limongelli, Massimo Petruzzi, Francesca Dimilito, Lorenzo Lo Muzio, Maria Eleonora Bizzoca, Giuseppina Campisi, Vera Panzarella, Stefania Leuci, Rosario Serpico, Alberta Lucchese, Giuseppe Colella, Giacomo Oteri, Antonia Marcianò, Gaetano Isola, Alessandro Polizzi, Amerigo Giudice, Elena Calabria, Umberto Mariani, Daniela Adamo, Federica Canfora, Filippo Graziani, Marco Nisi, Michele Giuliani, Luisa Ritrovato, Federica De Micheli, Cosimo Rupe, Francesco Scilla, Romeo Patini, Massimo Cordaro, Michele Davide Mignogna, Carlo Lajolo, SIPMO (Italian Society of Oral Pathology and Medicine)   +62 more
wiley   +1 more source

Protease inhibitors prevent plasminogen-mediated, but not pemphigus vulgaris-induced, acantholysis in human epidermis [PDF]

, 2003
Pemphigus is an autoimmune blistering disease of the skin and mucous membranes. It is caused by autoantibodies directed against desmosomes, which are the principal adhesion structures between epidermal keratinocytes.
Besch, R., Wosikowski, K., Probst, C., Sander, C. A., Degitz, K., Schuh, T., Flaig, M. J., Braungart, E., Douwes, K., Magdolen, V., C.A. Sander, C. Probst, K. Wosikowski, K. Degitz, T. Schuh, R. Besch, E. Braungart, V. Magdolen, M.J. Flaig, K. Douwes   +19 more
core   +2 more sources

Unraveling the autoimmune architecture of pemphigus: from B-cell depletion to network-based immune engineering

Frontiers in Immunology
Pemphigus encompasses autoimmune blistering diseases driven by autoantibodies to desmosomal proteins. Disruption of keratinocyte adhesion produces acantholysis and epidermal fragility.
Pedram Shafiei-Jahani, Pedram Shafiei-Jahani, Xin Li, Amitis Akbari, Anissa Vera, Emily Haniff, Ryan Carlisle, Ryan Carlisle, Omid Akbari, Vanessa Holland, Vanessa Holland   +10 more
doaj   +1 more source

Navigating the Complexities of Pemphigus Vulgaris: A Comprehensive Iranian Study

Immunity, Inflammation and Disease, Volume 14, Issue 2, February 2026.
We conducted a cross‐sectional analysis of 63 patients diagnosed with pemphigus vulgaris, confirmed by biopsy. Information was collected via telephone interviews. The research aimed to assess the demographic characteristics, initial symptoms, diagnosis delays, and treatment outcomes of the participants.
Delaram Moosavi, Seyed Mohammad Mahdi Khadem, Afsaneh Sadeghzadeh Bazargan, Kambiz Kamyab Hesari, Mehrnaz Azh, Hamed Zarei Sharif, Nasrin Shayanfar, Azadeh Goodarzi   +7 more
wiley   +1 more source