Results 151 to 160 of about 9,164 (166)

Is paraoxonase related to atherosclerosis

Chemico-Biological Interactions, 1993
Human serum paraoxonase is responsible for the hydrolysis of organophosphate anticholinesterases, however, whether the enzyme has a physiological role other than the detoxication of insecticides and nerve gases has remained uncertain. Recently, evidence has begun to accumulate of a relationship between the serum activity of paraoxonase and ...
Mackness, Michael I., Arrol, Sharon, Abbott, Caroline A., Durrington, Paul N.   +3 more
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Paraoxonase 1 and homocysteine metabolism

Amino Acids, 2012
Paraoxonase 1 (PON1), a component of high-density lipoprotein (HDL), is a calcium-dependent multifunctional enzyme that connects metabolisms of lipoproteins and homocysteine (Hcy). Both PON1 and Hcy have been implicated in human diseases, including atherosclerosis and neurodegeneration.
Joanna, Perła-Kaján, Hieronim, Jakubowski   +1 more
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Paraoxonase and coronary heart disease

Atherosclerosis Supplements, 2002
The antioxidant activity of HDL is largely due to the paraoxonase (PON1) located on it. Experiments with transgenic PON1 knock-out mice indicate the potential for PON1 to protect against atherogenesis. This effect of HDL in decreasing LDL lipid peroxidation is maintained for longer than that of antioxidant vitamins and could thus be more protective ...
Michael I, Mackness, Bharti, Mackness, Paul N, Durrington   +2 more
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Paraoxonase distribution in caucasian males

Chemico-Biological Interactions, 1993
Mean plasma paraoxonase activity was lower in a population of all males than in a mixed sex population with no evidence of the higher activity group. It is suggested that sex differences in plasma lipid may contribute to the observed differences, and that factors other than genetics may influence observed plasma paraoxonase levels.
F M, Williams, E, Mutch, P G, Blain
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Paraoxonase Activity in Athletic Adolescents

Pediatric Exercise Science, 2010
Regular physical activity may play a protective role against cardiovascular disease in adults, and paraoxonase activity may serve to mediate this effect. This study compared paraoxonase activity and that of other antioxidative agents in adolescent athletes compared with inactive youth.
Alpay, Cakmak, Dost, Zeyrek, Ali, Atas, Ozcan, Erel   +3 more
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Polymorphism of Human Serum Paraoxonase

1978
The insecticide parathion is metabolized in the organism as shown in Figure 1. An important reaction is the oxidation to paraoxon, which is very toxic to warmblooded and many other animals. Parathion and paraoxon are hydrolyzed in body fluids and organs. Of special interest today is the hydrolysis of paraoxon in human serum.
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Paraoxonases

2013
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Paraoxonase and atherosclerosis

Klinická biochemie a metabolismus, 2009
Z Ďuračková, L Andrezálová
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[Arylesterase, paraoxonase].

Nihon rinsho. Japanese journal of clinical medicine, 2005
Yukio, Ikeda, Tadashi, Suehiro
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Trimetazidine Activates Paraoxonase

American Journal Cardiovascular Drugs, 2010
Goran Pante Koracevic, Tatjana Cvetkovic, Maja Koracevic   +2 more
openaire   +1 more source