Results 131 to 140 of about 22,824 (262)

Effects of paraoxonase 1 gene polymorphisms on heart diseases

open access: yesMedicine, 2016
Background:Associations between paraoxonase 1 (PON1) gene polymorphisms and heart diseases (HD) risk remain inconsistent. In order to obtain address this issue we performed a meta-analysis to assess the association between the L55M and Q192R ...
Yazmín Hernández-Díaz   +7 more
semanticscholar   +1 more source

IMPACT OF CARBAZOLE P-LACTAM DERIVATIVES ON PARAOXONASE-1 ACTIVITY [PDF]

open access: yes, 2017
Paraoxonase 1 (PON1) is an antioxidant enzyme associated with high-density lipoproteins (HDL). PON1 has the ability to inhibit lipid peroxides and to hydrolyze a wide variety of substrates such as esters, thioesters, phosphotriesterases, carbonates ...
Arlinda Bytyqi-Damoni   +5 more
core  

Paraoxonase Activity and Genotype Predispose to Successful Aging [PDF]

open access: yes, 2017
The paraoxonase 1 codon 192 R allele has been previously reported to have a role in successful aging. The relationship between PON1 genotypes, enzymatic activity, and mass concentration was evaluated in a group of 229 participants from 22 to 104 years of
Marchegiani, Francesca   +9 more
core  

Paraoxonase 1 in patients with diabetes mellitus [PDF]

open access: yes, 2015
Humana serumska paraoksonaza 1 (PON1) je protein molekularne mase 43 kDa čija je katalitička aktivnost hidroliza organofosfatnih estera, aromatskih estera karboksilnih kiselina i karbamata.
Knežević, Josip
core  

Influence of paraoxonase-1 Q192R and cytochrome P450 2C19 polymorphisms on clopidogrel response [PDF]

open access: yes, 2012
Rolf P Kreutz1,2, Perry Nystrom2, Yvonne Kreutz2, Jia Miao2, Zeruesenay Desta2, Jeffrey A Breall1, Lang Li2, ChienWei Chiang2, Richard Kovacs1, David A Flockhart2, Yan Jin21Krannert Institute of Cardiology, 2Division of Clinical Pharmacology, Indiana ...
Breall JA   +10 more
core  

NOT PON1 L55M BUT ACE I/D VARIANT MIGHT BE A RISK FACTOR FOR OSCC IN THE TURKISH POPULATION

open access: yesSabiad
Objective: Oral squamous cell carcinoma (OSCC) covers more than 90% of the malignant neoplasms in the mouth. It has been shown that angiotensin-converting enzyme (ACE) and paraoxonase (PON1) gene variants were associated with several cancers.
Ayşe Feyda Nursal   +4 more
doaj   +1 more source

Do CO2 and oxidative stress induce cancer?: a brief study about the evaluation of PON 1, CAT, CA and XO enzyme levels on head and neck cancer patients

open access: yesJournal of Enzyme Inhibition and Medicinal Chemistry, 2019
Head and neck cancer (HNC) is one of the most common malignancies in the world. HNC is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands. According to this section of the body parts; induction of cancer can be
Murad Mutlu   +8 more
doaj   +1 more source

The paraoxonase Gln-Arg 192 polymorphism in subjects with ischaemic heart disease. [PDF]

open access: yes, 1997
BACKGROUND: Human serum paraoxonase activity is related to the paraoxonase Gln-Arg 192 polymorphism genotype. The purpose of this study was to investigate the association between the Gln-Arg 192 polymorphism of paraoxonase and ischaemic heart disease ...
Stickland, M H   +3 more
core   +2 more sources

The past and present of paraoxonase enzyme: Its role in the cardiovascular system and some diseases [PDF]

open access: yesJournal of Medical Biochemistry, 2012
Although paraoxonase is synthesized in many tissues including the heart, colon, kidneys, lungs, small intestines and brain, its major locus of synthesis is the liver.
Aydin Suleyman   +4 more
doaj  

Paraoxonase and Arylesterase Enzymatic Activities in Retinal Vein Occlusion Patients [PDF]

open access: yes, 2018
Amaç: Paraoksonaz enziminin retina ven tıkanıklığı ve kontrol gruplarında arilester ve paraoksonaz etkinliklerinin karşılaştırılması. Gereç ve Yöntem: Çalışmaya 38 retina ven tıkanıklığı hastası ve 38 cinsiyet ve yaş eşleştirilmiş gönüllü dahil edildi ...
Polat, Osman Ahmet   +4 more
core  

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