Results 121 to 130 of about 22,824 (262)

Active Site Hydrophobicity and the Convergent Evolution of Paraoxonase Activity in Structurally Divergent Enzymes: The Case of Serum Paraoxonase 1

open access: yesJournal of the American Chemical Society, 2016
Serum paraoxonase 1 (PON1) is a native lactonase capable of promiscuously hydrolyzing a broad range of substrates, including organophosphates, esters, and carbonates.
David Blaha-Nelson   +4 more
semanticscholar   +1 more source

Erva-matte (Ilex paraguariensis, St.Hil.) em cápsulas: estudos de toxicidade clínica e efeitos hipocolesterolêmico e antioxidante em indivíduos com dislipidemias [PDF]

open access: yes, 2013
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Farmácia, Florianópolis, 2013.Infusões de erva-mate (Ilex paraguariensis, St.
Becker, Aline Minuzzi
core  

Paraoxonase activity assessment in dogs suffering from Parvovirus infection [PDF]

open access: yes, 2021
ΔΕΝ ΔΙΑΤΙΘΕΤΑΙ ΠΕΡΙΛΗΨΗCanine Parvovirus enteritis is one of the most common causes of diarrhea and death in dogs younger than 6 months of age. Clinical gastroenteritis in parvo-positive dogs is associated with increased levels of lipid peroxides and ...
SALARPOUR, R.   +3 more
core   +1 more source

Lycopene Improves the Metformin Effects on Glycemic Control and Decreases Biomarkers of Glycoxidative Stress in Diabetic Rats

open access: yesDiabetes, Metabolic Syndrome and Obesity, 2020
Ingrid Delbone Figueiredo, Tayra Ferreira Oliveira Lima, Maiara Destro Inácio, Mariana Campos Costa, Renata Pires Assis, Iguatemy Lourenço Brunetti, Amanda Martins Baviera Department of Clinical Analysis, School of Pharmaceutical Sciences ...
Figueiredo ID   +6 more
doaj  

Serum paraoxonase activity is decreased in uremic patients [PDF]

open access: yes, 1996
Paraoxonase is a high-density lipoprotein (HDL)-associated enzyme capable of hydrolysing lipid peroxides. paraoxonase activity appears significantly reduced in hemodialyzed patients compared with 64 healthy ...
Biasoli S.   +5 more
core  

Assessment of Serum Level of Paraoxonase-1 in Patients with Psoriasis Vulgaris [PDF]

open access: yes, 2022
Background: Psoriasis is a chronic inflammatory dermatological disease with a strong genetic predisposition and autoimmune pathogenic traits. The hallmark of psoriasis is sustained inflammation that leads to uncontrolled keratinocyte proliferation and ...
Abo-Elsood, Karima Hussein Mohamed   +3 more
core   +1 more source

Current Therapies Focused on High-Density Lipoproteins Associated with Cardiovascular Disease

open access: yesMolecules, 2018
High-density lipoproteins (HDL) comprise a heterogeneous family of lipoprotein particles divided into subclasses that are determined by density, size and surface charge as well as protein composition.
Diego Estrada-Luna   +9 more
doaj   +1 more source

Decreased arylesterase activity of paraoxonase-1 (PON-1) might be a common denominator of neuroinflammatory and neurodegenerative diseases.

open access: yesInternational Journal of Biochemistry and Cell Biology, 2016
High-density lipoprotein (HDL)-bound paraoxonase-1 (PON-1) is mechanistically related to oxidative stress, inflammation and atherosclerosis and this multirole nature positions the enzyme as potential pathogenic player and candidate biomarker for many ...
M. Castellazzi   +10 more
semanticscholar   +1 more source

Serum paraoxonase status: A major factor in determining resistance to organophosphates [PDF]

open access: yes, 1993
A number of lines of evidence suggest that serum paraoxonase is protective against poisoning by organophosphorus substrates of this enzyme. Birds that have very low levels of paraoxon hydrolyzing activity in their sera are very susceptible to parathion ...
Li, Wan-Fen   +2 more
core   +1 more source

PON1 and PON3 in Alzheimer’s Disease: Similar Functions but Different Roles

open access: yesAntioxidants
Paraoxonase 1 (PON1) and Paraoxonase 3 (PON3) are enzymes located on the surface of high-density lipoprotein (HDL) and share similar antioxidant properties, possibly modulated by other proteins such as Myeloperoxidase (MPO), which drives the shift from ...
Alessandro Trentini   +8 more
doaj   +1 more source

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