Anti-apolipoprotein A-I antibodies and paraoxonase 1 activity in systemic lupus erythematosus [PDF]
, 2013 Systemic lupus erythematosus (SLE) patients have an increased risk of atherosclerosis. Identification of at-risk patients and the pathogenesis of atherosclerosis in SLE remain elusive. Paraoxonase 1 (PON1) and anti-apolipoprotein A-I antibody (anti-Apo A-
Ahmed, Mohammed Mahmoud +6 more
core
Effects of cumin extract on oxLDL, paraoxanase 1 activity, FBS, total cholesterol, triglycerides, HDL-C, LDL-C, Apo A1, and Apo B in in the patients with hypercholesterolemia. [PDF]
, 2014 OBJECTIVES Paraoxanase 1 (PON1) plays a protective role against the oxidative modification of plasma lipoproteins and hydrolyzes lipid peroxides in human atherosclerotic lesions.
Farrokhi, E., Ghatreh Samani, K.
core +3 more sources
Association between genetic polymorphisms and carotid atherosclerosis in patients treated with radiotherapy for nasopharyngeal carcinoma [PDF]
, 2015 published_or_final_versio
Cheuk, IW +5 more
core +2 more sources
The evaluation of accusation paraoxonase1 enzyme activity and its (-108, -126) polymorphisms in diabetic patients [PDF]
, 2017 Background and aims: Paraoxonase1 (PON1) is a liver-derived glycoprotein that is secreted into circulation. Among individuals in a population, PON1 activity varies widely.
Asgary, Sedigheh. +3 more
core
Implications of serum paraoxonase activity in obesity, diabetes mellitus, and dyslipidemia
Indian Journal of Endocrinology and Metabolism, 2013 Human serum paraoxonase 1 (PON1) is an enzyme with esterase activity, and is physically bound to high-density lipoproteins (HDL). It plays a key role in the action of HDL toward protection of lipoprotein and biological membrane against oxidative damage ...
Sunil K Kota +5 more
doaj +1 more source
The effects of Purslane (Portulaca oleracea L.) on serum level of lipids, lipoproteins and paraoxanase 1(PON1) activity in hypercholesterolemia patients [PDF]
, 2012 Some unverified reports around the world demonstrated that Purslane has therapeutic effects on some conditions. The aim of this study was to compare the effects of Purslane and Lovastatin therapy in decreasing serum lipids, lipoproteins, and paraoxanase1
Farrokhi, Effat. +4 more
core
NOT PON1 L55M BUT ACE I/D VARIANT MIGHT BE A RISK FACTOR FOR OSCC IN THE TURKISH POPULATION
SabiadObjective: Oral squamous cell carcinoma (OSCC) covers more than 90% of the malignant neoplasms in the mouth. It has been shown that angiotensin-converting enzyme (ACE) and paraoxonase (PON1) gene variants were associated with several cancers.
Ayşe Feyda Nursal +4 more
doaj +1 more source
Journal of Enzyme Inhibition and Medicinal Chemistry, 2019 Head and neck cancer (HNC) is one of the most common malignancies in the world. HNC is a group of cancers that starts in the mouth, nose, throat, larynx, sinuses, or salivary glands. According to this section of the body parts; induction of cancer can be
Murad Mutlu +8 more
doaj +1 more source
Study the relationship between Q192R paraoxonase gene polymorphism and high density lipoprotein composition after Lovastatin Trapy [PDF]
, 2012 زمینه و هدف: وظیفه آنتی اکسیدانی HDL به عهده آنزیـم پاراکسوناز 1 (PON1) می باشد. استاتین ها برغلظت و بیان ژن PON1 تاثیرگذار هستند. لذا اسیدهای چرب تشکیل دهنده فسفولیپیدها را در HDL دچار تغییر می کنند.
Farrokhi, Effat. +3 more
core
Oxidative stress products in type 2 diabetes and their relation to paraoxonase 1 activity [PDF]
, 2011 The present study indicated a significant increase in the serum advanced oxidn. protein products (AOPP) and malondialdehyde (MDA) a marker of lipid peroxidn., in diabetic group compared to control group. AOPP was found to be pos. correlated with MDA and
Ahmed Qahtan, . +2 more
core