Results 41 to 50 of about 6,578 (194)

Genotype-phenotype correlation in adult-onset acid maltase deficiency [PDF]

, 1995
We performed a clinical, biochemical, and genetic study in 16 patients from 11 families with adult‐onset acid maltase deficiency. All patients were compound heterozygotes and carried the IVS1(– 13T→G) transversion on one allele; the second allele ...
Amstel, H.K.P. van, Ausems, M.G.E.M. (Margreet), Boer, M.A. (Marijke), Boogaard, M.H. (Marie-José Henriëtte) van den, Diggelen, O.P. (Otto) van, Ippel, E.F., Jennekens, F.G.I. (Frans G.), Kroos, M.A. (Marian), Reuser, A.J.J. (Arnold), Wokke, J.H.J. (John)   +9 more
core   +1 more source

From Genomic and Epigenomic Maps to Medicines in Adult T‐Cell Leukemia/Lymphoma

Cancer Science, Volume 117, Issue 2, Page 289-296, February 2026.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive and refractory hematologic malignancy that is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. ATL results from a combination of viral latency and the accumulation of abnormalities throughout the genome, epigenome, transcriptome, and signaling pathways.
Kako Suzuki, Makoto Yamagishi
wiley   +1 more source

Human T-Lymphotropic Virus-1–Associated Myelopathy/Tropical Spastic Paraparesis Is Associated With Sexual Dysfunction in Infected Women of Reproductive Age

Sexual Medicine, 2018
Introduction: Human T-lymphotropic virus (HTLV)-1–associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a neurological disorder that mostly affects women.
Adenilda Lima Lopes Martins, MD, PhD, Maria Fernanda Rios Grassi, MD, PhD, Alisson de Aquino Firmino, MSc, Jean Paulo Lacerda Araujo, UGS, Taiane Silva Paixao, UGS, Bernardo Galvão-Castro, MD, PhD, Ney Boa-Sorte, MD, PhD   +6 more
doaj   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr., Georgii B. Telegin, Aleksandr S. Chernov, Anna A. Kudriaeva, Alexey N. Minakov, Maksim V. Rodionov, Vitaly A. Kazakov, Viktor A. Palikov, Yuri M. Poluektov, Rustam H. Ziganshin, Daria A. Orlova, Alena S. Evpak, Daniil A. Barsuk, Fedor A. Mesheryakov, Aldo Spallone, Dmitry S. Asyutin, Igor N. Pronin, Nikolay A. Konovalov, Dmitri Yu Usachev, Alexander G. Gabibov, Alexander N. Konovalov   +20 more
wiley   +1 more source

Is the innate bio-protection power against human virus the same between males and females? A conclusion based on blood donor data of HTLV-I infection [PDF]

, 2008
Human T-cell leukemia virus type I (HTLV-I) is a retrovirus that causes adult T-cell leukemia. The male-to-female transmission is stronger than the reverse, so the carrier proportion of women is greater than that of men.
Minoru Tabata, Nobuoki Eshima, Shigeru Karukaya, Yasunori Higuchi   +3 more
core   +1 more source

Drivers of Grass Pea (Lathyrus sativus L.) Market Supply and Its Sustainability Payoffs: Evidence From Jama District, Ethiopia

Legume Science, Volume 7, Issue 4, December 2025.
ABSTRACT Grass pea (Lathyrus sativus L.) is a climate‐smart legume crop widely grown in Ethiopia, well‐known for its resilience to abiotic stresses, and serves as an insurance crop. Despite its ecological and agronomic benefits, the crop's market supply remains underexplored from both economic and sustainability perspectives.
Yosef Worku Yigezu, Zenebu Shewakena Sidell, Tessema Astatkie   +2 more
wiley   +1 more source

Approach to a case of myeloneuropathy

Annals of Indian Academy of Neurology, 2016
Myeloneuropathy is a frequently encountered condition and often poses a diagnostic challenge. A variety of nutritional, toxic, metabolic, infective, inflammatory, and paraneoplastic disorders can present with myeloneuropathy. Deficiencies of vitamin B12,
Ravindra Kumar Garg, Hardeep Singh Malhotra, Neeraj Kumar   +2 more
doaj   +1 more source

HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis Overlapping Ossification of the Ligamentum Flavum

Indian Journal of Neurosurgery, 2020
HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is an important cause of nontraumatic and noncompressive chronic myelopathy which generally has no improvement regardless of treatment.
Guilherme Gago, Luidia Varrone Giacomini, Frederico de Lima Gibbon, Euripedes Gomes de Carvalho Neto, Fernando Kowacs, Nelson Pires Ferreira   +5 more
doaj   +1 more source

HTLV-1-associated myelopathy/tropical spastic paraparesis

Nature Reviews Disease Primers, 2015
Human T-lymphotropic virus 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive disease of the CNS that causes weakness or paralysis of the legs, lower back pain and urinary symptoms. HAM/TSP was first described in Jamaica in the nineteenth century, but the aetiology of the condition, infection with the retrovirus ...
Bangham, CRM, Araujo, A, Yamano, Y, Taylor, GP   +3 more
openaire   +4 more sources

HTLV-I associated myelopathy / tropical spastic paraparesis: report of the first cases in Rio Grande do Sul, Brazil Mielopatia associada ao HTLV-I/paraparesia espástica tropical: relato dos primeiros casos no Rio Grande do Sul, Brasil

Arquivos de Neuro-Psiquiatria, 1995
The HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP), a myelopathy with predominant involvement of the pyramidal tract with minimal sensory loss and associated with HTLV-I infection, endemic in tropical areas, has been identified in ...
Sérgio Roberto Haussen, Maria Cecilia de Vecino   +1 more
doaj   +1 more source