Results 51 to 60 of about 6,479 (214)

Functional impairment of Tax-specific but not cytomegalovirus-specific CD8+ T lymphocytes in a minor population of asymptomatic human T-cell leukemia virus type 1-carriers [PDF]

, 2011
Background Human T-cell leukemia virus type 1 (HTLV-1) causes adult T-cell leukemia (ATL) and HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a small percentage of infected individuals.
Ayako Takamori, Atsuhiko Hasegawa, Atae Utsunomiya, Yasuhiro Maeda, Yoshihisa Yamano, Masato Masuda, Yukiko Shimizu, Yotaro Tamai, Amane Sasada, Na Zeng, Ilseung Choi, Naokuni Uike, Jun Okamura, Toshiki Watanabe, Takao Masuda, Mari Kannagi   +15 more
core   +2 more sources

From Genomic and Epigenomic Maps to Medicines in Adult T‐Cell Leukemia/Lymphoma

Cancer Science, Volume 117, Issue 2, Page 289-296, February 2026.
ABSTRACT Adult T‐cell leukemia/lymphoma (ATL) is an aggressive and refractory hematologic malignancy that is caused by human T‐cell leukemia virus type‐1 (HTLV‐1) retrovirus. ATL results from a combination of viral latency and the accumulation of abnormalities throughout the genome, epigenome, transcriptome, and signaling pathways.
Kako Suzuki, Makoto Yamagishi
wiley   +1 more source

HTLV-I associated myelopathy / tropical spastic paraparesis: report of the first cases in Rio Grande do Sul, Brazil Mielopatia associada ao HTLV-I/paraparesia espástica tropical: relato dos primeiros casos no Rio Grande do Sul, Brasil

Arquivos de Neuro-Psiquiatria, 1995
The HTLV-I associated myelopathy/tropical spastic paraparesis (HAM/TSP), a myelopathy with predominant involvement of the pyramidal tract with minimal sensory loss and associated with HTLV-I infection, endemic in tropical areas, has been identified in ...
Sérgio Roberto Haussen, Maria Cecilia de Vecino   +1 more
doaj   +1 more source

Repurposing of Chemokine Antagonists for Combined Phase‐Resolved Spinal Cord Injury Treatment

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Spinal cord injury (SCI) in mammals is accompanied by a massive cytokine storm in cerebrospinal fluid, mainly driven by CXCL1, IL‐6, and CCL2‐5. Sub‐acute phase is mostly associated with IL‐2, IL‐7, CCL22, and CX3CL1, whereas TNFα and IL17α permanently persists in CNS even weeks following SCI.
Alexey A. Belogurov Jr., Georgii B. Telegin, Aleksandr S. Chernov, Anna A. Kudriaeva, Alexey N. Minakov, Maksim V. Rodionov, Vitaly A. Kazakov, Viktor A. Palikov, Yuri M. Poluektov, Rustam H. Ziganshin, Daria A. Orlova, Alena S. Evpak, Daniil A. Barsuk, Fedor A. Mesheryakov, Aldo Spallone, Dmitry S. Asyutin, Igor N. Pronin, Nikolay A. Konovalov, Dmitri Yu Usachev, Alexander G. Gabibov, Alexander N. Konovalov   +20 more
wiley   +1 more source

PERFORMANCE OF THE GAIT IN INDIVIDUALS WITH HTLV-1: SYSTEMATIC REVIEW

Revista Pesquisa em Fisioterapia, 2017
HTLV-1 is frequently associated with myelopathy/tropical spastic paraparesis (HAM/TSP), which in turn brings several functional alterations to the individual, including changes in gait.
Mateus Evangelista do Amparo Santana, Livia Aguiar Pereira, Rafael Monteiro, Erika Pedreira Fonseca   +3 more
doaj   +1 more source

Genotype-phenotype correlation in adult-onset acid maltase deficiency [PDF]

, 1995
We performed a clinical, biochemical, and genetic study in 16 patients from 11 families with adult‐onset acid maltase deficiency. All patients were compound heterozygotes and carried the IVS1(– 13T→G) transversion on one allele; the second allele ...
Amstel, H.K.P. van, Ausems, M.G.E.M. (Margreet), Boer, M.A. (Marijke), Boogaard, M.H. (Marie-José Henriëtte) van den, Diggelen, O.P. (Otto) van, Ippel, E.F., Jennekens, F.G.I. (Frans G.), Kroos, M.A. (Marian), Reuser, A.J.J. (Arnold), Wokke, J.H.J. (John)   +9 more
core   +1 more source

Telomere Length, Proviral Load and Neurologic Impairment in HTLV-1 and HTLV-2-Infected Subjects. [PDF]

, 2016
Short or damaged telomeres have been implicated in degenerative conditions. We hypothesized that analysis of telomere length (TL) in human T-cell lymphotropic virus (HTLV) infection and HTLV-associated neuropathy might provide clues to the etiology of ...
Blackburn, Elizabeth, Bruhn, Roberta, Lee, Tzong-Hae, Lin, Jue, Murphy, Edward L, Usadi, Benjamin   +5 more
core   +3 more sources

Tropical spastic paraparesis.

Folia neuropathologica, 2002
Human T-cell lymphotropic virus type I (HTLV-I) is the cause of endemic tropical spastic paraparesis (TSP) or HTLV-I-associated myelopathy (HAM). Because TSP/HAM is not a fatal disease, the neuropathology of this disease, albeit relatively well understood, is based on the examination of just a few incidental cases.
J, Buczyński, R, Yanagihara, C, Mora, L, Cartier, A, Verdugo, F, Araya, L, Castillo, C J, Gibbs, C D, Gajdusek, P, Rogers-Johnson, P P, Liberski   +10 more
openaire   +1 more source

Drivers of Grass Pea (Lathyrus sativus L.) Market Supply and Its Sustainability Payoffs: Evidence From Jama District, Ethiopia

Legume Science, Volume 7, Issue 4, December 2025.
ABSTRACT Grass pea (Lathyrus sativus L.) is a climate‐smart legume crop widely grown in Ethiopia, well‐known for its resilience to abiotic stresses, and serves as an insurance crop. Despite its ecological and agronomic benefits, the crop's market supply remains underexplored from both economic and sustainability perspectives.
Yosef Worku Yigezu, Zenebu Shewakena Sidell, Tessema Astatkie   +2 more
wiley   +1 more source

Danazol a new perspective in the treatment of htlv-l associated myelopathy (preliminary report)

Arquivos de Neuro-Psiquiatria, 1992
We investigated the efficacy of danazol treatment in eight patients with HTLV-l associated myelopathy/tropical spastic paraparesis (HAM/TSP). Treatment with danazol yielded clinical improvement of urinary control and gait disturbances in 7 out of the 8 ...
Ailton Melo, Luciana Moura, Ana Meireles, Gerçonita Costa   +3 more
doaj   +1 more source