Parathyroid hormone secretion is controlled by both ionized calcium and phosphate during exercise and recovery in men [PDF]
, 2016 Context: The mechanism by which PTH is controlled during and after exercise is poorly understood due to insufficient temporal frequency of measurements.
Currell, Kevin +7 more
core +1 more source
The calcium-sensing receptor regulates parathyroid hormone gene expression in transfected HEK293 cells [PDF]
, 2009 Background The parathyroid calcium receptor determines parathyroid hormone secretion and the response of parathyroid hormone gene expression to serum Ca2+ in the parathyroid gland.
Galitzer, Hillel +5 more
core +3 more sources
PTH1R-CaSR Cross Talk: New Treatment Options for Breast Cancer Osteolytic Bone Metastases. [PDF]
, 2018 Metastatic breast cancer (BrCa) is currently incurable despite great improvements in treatment of primary BrCa. The incidence of skeletal metastases in advanced BrCa occurs up to 70%.
Wang, Bin, Yang, Yanmei
core +2 more sources
Effects of etelcalcetide on fibroblast growth factor 23 in patients with secondary hyperparathyroidism receiving hemodialysis [PDF]
, 2019 Background: Etelcalcetide is an intravenous calcimimetic approved for treatment of secondary hyperparathyroidism (sHPT) in patients receiving hemodialysis. Besides lowering parathyroid hormone (PTH), etelcalcetide also significantly reduces fibroblast
Block, Geoffrey A. +9 more
core +1 more source
Alkaline phosphatases in the complex chronic kidney disease-mineral and bone disorders [PDF]
, 2018 Alkaline phosphatases (APs) remove the phosphate (dephosphorylation) needed in multiple metabolic processes (from many molecules such as proteins, nucleotides, or pyrophosphate). Therefore, APs are important for bone mineralization but paradoxically they
Aguilar, Armando +8 more
core +1 more source
Parathyroid hormone-related peptide stimulates intestinal strontium absorption in Camels (Camelus dromedarius) [PDF]
, 2008 The present work was undertaken to evaluate the stimulatory effect of Parathyroid hormone-related peptide (PTHrP) on the intestinal calcium (Ca) absorption using stable strontium (Sr) as a surgoate marker in 10 Camels.
Coxam, Véronique +7 more
core
Positioning novel biologicals in CKD-mineral and bone disorders [PDF]
, 2017 Renal osteodystrophy (ROD), the histologic bone lesions of chronic kidney disease (CKD), is now included in a wider syndrome with laboratory abnormalities of mineral metabolism and extra-skeletal calcifications or CKD-mineral and bone disorders (CKD-MBD),
Covic, Adrian +5 more
core +1 more source
Biosynthesis of Proparathyroid Hormone and Parathyroid Hormone by Human Parathyroid Glands [PDF]
Journal of Clinical Investigation, 1973 Human parathyroid glands obtained at autopsy were incubated with [(3)H]leucine and [(3)H]lysine. After incubation, nonradioactive parathyroid tissue of either human or bovine origin was added. Radioactive parathyroid hormone and proparathyroid hormone were isolated from the gland and medium by organic solvent and salt fractionation, trichloroacetic ...
David V. Cohn +4 more
openaire +3 more sources
Active vitamin D (1,25-dihydroxyvitamin D) and bone health in middle-aged and elderly men: the European male aging study (EMAS) [PDF]
, 2013 <p>Context: There is little information on the potential impact of serum 1,25-dihydroxyvitamin D [1,25(OH)2D] on bone health including turnover.</p> <p>Objective: The objective of the study was to determine the influence of 1,25(OH ...
Akhter +67 more
core +3 more sources
Efficacy of Ultrasound-guided Radiofrequency Ablation of Parathyroid Hyperplasia: Single Session vs. Two-Session for Effect on Hypocalcemia [PDF]
, 2020 To evaluate safety and efficacy of one- vs. two-session radiofrequency ablation (RFA) of parathyroid hyperplasia for patients with secondary hyperparathyroidism (SHPT) and to compare the outcome of both methods on hypocalcemia.
He, Hong-Feng +7 more
core +1 more source