The calcium-sensing receptor as a regulator of cellular fate in normal and pathological conditions [PDF]
, 2013 The calcium-sensing receptor (CaSR) belongs to the evolutionarily conserved family of plasma membrane G protein-coupled receptors (GPCRs). Early studies identified an essential role for the CaSR in systemic calcium homeostasis through its ability to ...
Benoit, Yves +3 more
core +1 more source
PTHrP treatment of colon cancer cells promotes tumor associated-angiogenesis by the effect of VEGF [PDF]
, 2019 We showed that Parathyroid Hormone-related Peptide (PTHrP) induces proliferation, migration, survival and chemoresistance via MAPKs and PI3K/AKT pathways in colorectal cancer (CRC) cells.
Calvo, Natalia Graciela +4 more
core +1 more source
Evidence-Based Laboratory: Determining the Insufficiency Level of Vitamin D
Haseki Tıp Bülteni, 2016 Aim: There is lack of studies on the relationship between parathyroid hormone and vitamin D levels for defining deficiency and insufficiency of vitamin D in adults living in Turkey.
Eren Vurgun +2 more
doaj +1 more source
The anabolic action of intermittent parathyroid hormone on cortical bone depends partly on its ability to induce nitric oxide-mediated vasorelaxation in BALB/c mice [PDF]
, 2016 There is strong evidence that vasodilatory nitric oxide (NO) donors have anabolic effects on bone in humans. Parathyroid hormone (PTH), the only osteoanabolic drug currently approved, is also a vasodilator.
Bukoski RD +6 more
core +2 more sources
A Case of Mediastinal Parathyroid Adenoma
Haseki Tıp Bülteni, 2015 Parathyroid adenomas are the most important cause of primary hyperparathyroidism. The diagnosis of primary hyperparathyroidism is established based on the combination of elevated serum calcium and parathyroid hormone levels.
Erkan Akar
doaj +1 more source
The significance of determining the Intraoperative level of parathormone during surgical treatment of hyperparathyroidism [PDF]
Hospital PharmacologyIntroduction: Surgical treatment is the method of choice for treating primary hyperparathyroidism. Determining parathyroid hormone (PTH) levels intraoperatively allows for real-time monitoring of the functional activity of parathyroid gland tissue and ...
Janičić Stefan D. +8 more
doaj +1 more source
Novel Criteria for Parathyroid Hormone Levels in Parathyroid Hormone–Guided Parathyroid Surgery
Archives of Pathology & Laboratory Medicine, 2007 Abstract Context.—Novel criteria for decrease of perioperative parathyroid hormone measurement may improve the accuracy of perioperative quick parathyroid hormone (qPTH)–guided parathyroidectomy. Objective.—To assess overall cure rate based on conventional criteria (50% decline of qPTH).
Wouter W. de Herder +5 more
openaire +5 more sources
Alkaline phosphatases in the complex chronic kidney disease-mineral and bone disorders [PDF]
, 2018 Alkaline phosphatases (APs) remove the phosphate (dephosphorylation) needed in multiple metabolic processes (from many molecules such as proteins, nucleotides, or pyrophosphate). Therefore, APs are important for bone mineralization but paradoxically they
Aguilar, Armando +8 more
core +1 more source
Parathyroid hormone secretion is controlled by both ionized calcium and phosphate during exercise and recovery in men [PDF]
, 2016 Context: The mechanism by which PTH is controlled during and after exercise is poorly understood due to insufficient temporal frequency of measurements.
Currell, Kevin +7 more
core +1 more source
SAGE Open Medical Case Reports, 2020 The diagnosis of extrapulmonary tuberculosis in patients with end-stage renal disease can be challenging as the signs and symptoms are often non-specific.
Shreya Podder +2 more
doaj +1 more source