Follicular nodules (Thy3) of the thyroid: is total thyroidectomy the best option? [PDF]
, 2014 BACKGROUND: Identification of the best management strategy for nodules with Thy3 cytology presents particular problems for clinicians. This study investigates the ability of clinical, cytological and sonographic data to predict malignancy in ...
CALO', PIETRO GIORGIO +6 more
core +1 more source
Molecular pathology of endocrine gland tumors: genetic alterations and clinicopathologic relevance [PDF]
, 2023 Tumors of the endocrine glands are common. Knowledge of their molecular pathology has greatly advanced in the recent past. This review covers the main molecular alterations of tumors of the anterior pituitary, thyroid and parathyroid glands, adrenal ...
Coluccelli, Sara +6 more
core +1 more source
Senescent cells: A therapeutic target for osteoporosis
Cell Proliferation, Volume 55, Issue 12, December 2022., 2022 Bone is a metabolically active tissue involved in physiological processes of locomotion, support and protection of soft tissues, calcium and phosphate storage, and harbouring of bone marrow. Bone is constituted by various types of cells undergoing continuous remodelling.
Tiantian Wang, Shishu Huang, Chengqi He
wiley +1 more source
Frontiers in Endocrinology, 2018 Thyroid tumors usually present as masses in the thyroid gland. While the majority of these tumors represent neoplasms of thyroid tissues, mainly of follicular epithelial cell differentiation, the differential diagnosis includes other lesions, such as C ...
Sylvia L. Asa +3 more
doaj +1 more source
Bilateral Genu Valgum in an Adolescent with Primary Hyperparathyroidism
Journal of the ASEAN Federation of Endocrine Societies, 2020 Primary hyperparathyroidism in children and adolescents is rare and often symptomatic at presentation. A 15-year-old boy presented with bilateral genu valgum for two years. Biochemical results were consistent with primary hyperparathyroidism.
Siow Ping Lee +3 more
doaj +1 more source
A late diagnosis of MEN 1 Syndrome in a young patient initially pre-senting with nephrolithiasis
Liječnički vjesnik, 2023 Multiple Endocrine Neoplasms Type 1 (MEN 1), originally called Wermer Syndrome, is a rare hereditary condition caused by mutations in the MEN1 tumor suppressor gene.
Ana Čala, Tina Dušek
doaj +1 more source
Mathematical models for order of mutation problem in myeloproliferative neoplasm: non-additivity and non-commutativity [PDF]
arXiv, 2023 In some patients of myeloproliferative neoplasm, two genetic mutations can be found: JAK2 V617F and TET2. When one mutation is present or not, the other mutation has different effects on regulating gene expressions. Besides, when both mutations are present, the order of occurrence might make a difference.
arxiv
Ectopic Mediastinal Parathyroid Adenoma in a Patient with Chronic Kidney Disease: A Case Report
대한영상의학회지, 2019 We report an ectopic mediastinal parathyroid adenoma in a patient with chronic kidney disease who presented with refractory hypercalcemia. Technetium-99m-sestamibi scintigraphy is a valuable imaging technique for the detection of an ectopic parathyroid ...
Dong Min Choo +2 more
doaj +1 more source
Order-of-mutation effects on cancer progression: models for myeloproliferative neoplasm [PDF]
arXiv, 2023 We develop a modeling framework for cancer progression that distinguishes the order of two possible mutations. Recent observations and information on myeloproliferative neoplasms are analyzed within our framework. In some patients with myeloproliferative neoplasms, two genetic mutations can be found, JAK2 V617F and TET2.
arxiv
Towards Understanding the Survival of Patients with High-Grade Gastroenteropancreatic Neuroendocrine Neoplasms: An Investigation of Ensemble Feature Selection in the Prediction of Overall Survival [PDF]
, 2023 Determining the most informative features for predicting the overall survival of patients diagnosed with high-grade gastroenteropancreatic neuroendocrine neoplasms is crucial to improve individual treatment plans for patients, as well as the biological understanding of the disease. Recently developed ensemble feature selectors like the Repeated Elastic
arxiv +1 more source