Results 91 to 100 of about 2,189,457 (236)

A C‐Nucleoside Analogue of Cordycepin With High Metabolic Stability and Potent Anti‐Psoriatic Activity via Microneedle Delivery

open access: yesAdvanced Science, EarlyView.
This work identified CPD3a as a potent, stable C‐nucleoside cordycepin derivative. When formulated into microneedle array for topical treatment, it ameliorated psoriasis by rebalancing immunity and enhancing antioxidant defenses. ABSTRACT Psoriasis is a chronic inflammatory disorder characterized by immune dysregulation and epidermal hyperplasia ...
Wenfang Pan   +7 more
wiley   +1 more source

Perinatal Predictors and Mediators of Attachment Patterns in Preschool Children: Exploration of Children’s Contributions in Interactions with Mothers

open access: yesChildren
Insecure and disorganized attachment patterns in children are linked to poor health outcomes over the lifespan. Attachment patterns may be predicted by variables that influence the quality of children’s interactions with their primary caregivers/parents (
Stefan Kurbatfinski   +4 more
doaj   +1 more source

Toward Material‐Specific Peptides From in Silico Guided Peptide Engineering to Target PET in the Presence of PS

open access: yesAdvanced Science, EarlyView.
This work presents a computational–experimental strategy to engineer material‐binding peptides toward polymer specificity. Molecular dynamics simulations identified residues driving polystyrene binding, enabling targeted substitutions that greatly reduced polystyrene affinity while preserving PET binding.
Julian Luka   +3 more
wiley   +1 more source

Modeling of mobile phobia among students based on the quality of parent-child relationship and attachment styles: the mediating role of loneliness [PDF]

open access: yesروانشناسی و روانپزشکی شناخت
Introduction: Nomophobia is characterized by intense fear or anxiety resulting from being without access to a mobile phone, potentially impacting mental health and behavior. Objective: This study aimed to model nomophobia in high school students based on
Seyedeh Samane Mousavi Nasr   +1 more
doaj  

Hostile attributional style, mentalisation and attachment in preadolescence. [PDF]

open access: yes, 2005
This review aims to explore social information processing styles, mentalisation abilities, and attachment security, and their associations, in relation to aggressive behaviours.
Nelson, L.
core  

TRPC3‐Driven Calcium Microdomains Instruct Peripheral Nerve Regeneration With Protective Implications for Central Neurons

open access: yesAdvanced Science, EarlyView.
How localized Ca2+ signals orchestrate neural repair remains unclear. Here, we show that TRPC3‐driven calcium microdomains direct nerve repair by coupling spatially confined Ca2+ signals to axon regeneration. This module operates in injured peripheral neurons and correlates with neuroprotection in Parkinson's disease, revealing a spatial logic for ...
Yu Lu   +14 more
wiley   +1 more source

Investigating the effect of depression, stress, and attachment style on leftward cradling bias. [PDF]

open access: yes, 2013
The majority of women cradle infants to the left of their midline ? this phenomenon is known as leftward cradling bias. The right hemisphere's specialization for emotional processing is believed to explain the bias as it would facilitate emotional ...
McGrath, Margaret J
core   +1 more source

One‐Step Immobilized Phage Depolymerase Coatings for Catheter‐Related Bloodstream Infections

open access: yesAdvanced Science, EarlyView.
Catheter‐related bloodstream infections (CRBSI) caused by drug‐resistant Gram‐negative bacteria remain a major clinical challenge. Here, a polydopamine‐assisted depolymerase coating degrades bacterial capsules and restores serum‐mediated killing, effectively suppressing biofilms and reducing bacterial burden in vitro, ex vivo, and in vivo, presenting a
Lingkai Dong   +11 more
wiley   +1 more source

Children's mental representations of attachment: associations with attachment security and parent-child narrative quality [PDF]

open access: yes, 2011
The goal of this study was to examine the antecedents and correlates of children’s mental representations of attachment at 5 years (Attachment Story Completion Task, Bretherton, Ridgeway, & Cassidy, 1990; MacArthur Story Stem Battery, Bretherton ...
Wong, Maria S.
core  

Sequential Patterning of Photoresponsive Hydrogels Directs Crypt Fission and Reveals the Role of Epithelial Curvature on Fission Symmetry

open access: yesAdvanced Science, EarlyView.
Deterministic crypt fission is achieved in intestinal organoids using photopatternable hydrogels with spatiotemporal control. Daughter‐crypt symmetry is shown to depend on parent‐crypt geometry and epithelial curvature, while myosin‐dependent mechanosensing links tissue shape to regenerative outcomes.
Delaney L. McNally   +8 more
wiley   +1 more source

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