Results 91 to 100 of about 5,810,137 (395)

Parental Quality of Life in the Framework of Paediatric Chronic Gastrointestinal Disease [PDF]

, 2011
Chronic gastrointestinal diseases, such as inflammatory bowel disease (IBD) and celiac disease (CD), might have impact not only on the affected child but also on their parents since inside the family framework, a change in each member may have influence ...
Milan Nikšić, Radenka Munjas Samarin, Rajna Knez, Tanja Frančišković   +3 more
core   +4 more sources

Integrative miRNOMe profiling reveals the miR‐195‐5p–CHEK1 axis and its impact on luminal breast cancer outcomes

Molecular Oncology, EarlyView.
In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková, Marie Ehrlichová, Alžběta Spálenková, Ivona Krus, Simona Šůsová, Viktor Hlaváč, Vlasta Němcová, Renata Koževnikovová, Markéta Trnková, David Vrána, Jiří Gatěk, Kateřina Kopečková, Marcela Mrhalová, Soňa Měšťáková, Pavel Souček   +14 more
wiley   +1 more source

Analysis of pilot data assessing vaccine hesitancy in an urban clinic setting [PDF]

, 2018
Widespread use of childhood vaccination has significantly reduced the burden of childhood disease, however a subset of parents are choosing to delay or refuse available vaccines.
Williams, Amelia
core  

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

Molecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides, Sara Cristobal‐Vargas, Cristina De Ramón, Elizabeta A. Rojas, Irena Misiewicz‐Krzeminska, Isabel Isidro, José Juan Pérez, Bruno Paiva, Noemi Puig, Miguel Alcoceba, María‐Victoria Mateos, Luis A. Corchete, Myriam Cuadrado, Norma C. Gutiérrez   +13 more
wiley   +1 more source

The newborn behavioural observations (NBO) system embedded in routine postpartum care in at-risk families in Iceland: a randomised controlled trial

BMC Pregnancy and Childbirth
Background The Newborn Behaviour Observation system (NBO) is a flexible relationship-based intervention designed to sensitise parents to their newborn’s capacities, to increase parental confidence and foster the bond between parent and infant. The aim of
Lisbeth Valla, Kari Slinning, Tore Wentzel-Larsen, Gun-Mette Røsand, Stefanía Birna Arnardóttir   +4 more
doaj   +1 more source

Stuck Outside and Inside: An Exploratory Study on the Effects of the COVID-19 Outbreak on Italian Parents and Children’s Internalizing Symptoms

Frontiers in Psychology, 2020
The Covid-19 outbreak and the subsequent lockdown have profoundly impacted families’ daily life, challenging their psychological resilience. Our study aimed to investigate the immediate psychological consequences of the pandemic on Italian parents and ...
Cristiano Crescentini, Susanna Feruglio, Susanna Feruglio, Alessio Matiz, Andrea Paschetto, Enrico Vidal, Paola Cogo, Franco Fabbro   +7 more
doaj   +1 more source

Good-parent beliefs of parents of seriously ill children.

JAMA pediatrics, 2015
IMPORTANCE Parents' beliefs about what they need to do to be a good parent when their children are seriously ill influence their medical decisions, and better understanding of these beliefs may improve decision support.
C. Feudtner, J. Walter, J. Faerber, Douglas L. Hill, Karen W. Carroll, C. Mollen, Victoria A. Miller, W. Morrison, D. Munson, T. Kang, P. Hinds   +10 more
semanticscholar   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

Molecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero, Alejandro Belmonte‐Fernández, Mónica González‐Moreno, Laura Rodríguez‐Cordero, Begoña Pérez‐Valderrama, Joaquín Herrero‐Ruíz, Francisco Romero, Carmen Sáez, Miguel Á. Japón   +8 more
wiley   +1 more source

Cross-Sectional associations between inner setting determinants of self-efficacy and intent to deliver a healthy eating and activity curriculum embedded in a community setting

International Journal of Behavioral Nutrition and Physical Activity
Background Healthy Eating and Active Living Taught at Home (HEALTH) embeds healthy eating and activity content within Parents as Teachers (PAT), a national home visiting program.
Rachel G. Tabak, Cynthia D. Schwarz, Allison Kemner, Debra Haire-Joshu   +3 more
doaj   +1 more source

A qualitative study of parents' experiences using family support services: applying the concept of surface and depth [PDF]

, 2014
UK policy and practice endorses family support for child well-being. Achieving such support requires multi-agency approaches, that consider all aspects of parents’ and children’s lives and which offer practical, social and emotional help.
Cocker, Karen, Cox, Pat, Thomas, Nigel, Whittaker, Karen   +3 more
core   +1 more source