PARP1 and PARylation facilitate transcription-coupled DNA repair by stabilizing the CSB-RNAPII complex. [PDF]
Robu M +11 more
europepmc +1 more source
Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels. [PDF]
Cherdyntseva V +11 more
europepmc +1 more source
Family-wide analysis of human macrodomains reveals novel activities and identifies PARG as most efficient ADPr-RNA hydrolase. [PDF]
Weixler L +9 more
europepmc +1 more source
Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-strand break formation in <i>C. elegans</i>. [PDF]
Raices M +10 more
europepmc +1 more source
Interplay of replication stress response and immune microenvironment in high-grade serous ovarian cancer. [PDF]
Venegas L, Lheureux S.
europepmc +1 more source
The alternative lengthening of telomeres pathway through a DNA repair lens: mechanism and therapeutic opportunities. [PDF]
Muoio D, Fouquerel E.
europepmc +1 more source
Genetic evidence for PARP1 trapping as a driver of PARP inhibitor efficacy in BRCA mutant cancer cells. [PDF]
Ribeiro J +14 more
europepmc +1 more source
BARD1: A Friend or Foe in Pancreatic Ductal Adenocarcinoma? [PDF]
Zekavat L, Jain A.
europepmc +1 more source
Exploiting synthetic lethality in epithelial ovarian cancer: multi-dimensional approaches beyond DNA damage repair. [PDF]
Bigdeli M +4 more
europepmc +1 more source
Deltex and RING-UIM E3 ligases cooperate to create a ubiquitin-ADP-ribose hybrid mark on tankyrase, promoting its stabilization. [PDF]
Perrard J, Gao K, Ring K, Smith S.
europepmc +1 more source

