Results 121 to 130 of about 6,510 (175)

Nucleoplasmic Lamin A/C controls replication fork restart upon stress by modulating local H3K9me3 and ADP-ribosylation levels. [PDF]

Nat Commun
Cherdyntseva V, Paulson J, González-Acosta D, Ubieto-Capella P, Rodrigues M, Aouami M, Adakli S, Gagné JP, Bakker C, Poirier GG, Taneja N, Lopes M.   +11 more
europepmc   +1 more source

The alternative lengthening of telomeres pathway through a DNA repair lens: mechanism and therapeutic opportunities. [PDF]

NAR Cancer
Muoio D, Fouquerel E.
europepmc   +1 more source

Genetic evidence for PARP1 trapping as a driver of PARP inhibitor efficacy in BRCA mutant cancer cells. [PDF]

Nucleic Acids Res
Ribeiro J, Hansen K, van Beek L, Stubbs C, Frigola J, Talbot S, Bentouati S, Hall J, Wijnhoven PWG, Armenia J, Schimpl M, Forment JV, Albertella MR, O'Connor MJ, Illuzzi G.   +14 more
europepmc   +1 more source

Genetic and physical interactions reveal overlapping and distinct contributions to meiotic double-strand break formation in <i>C. elegans</i>. [PDF]

Elife
Raices M, Balmir F, Silva N, Li W, Grundy MK, Hoffman DK, Altendorfer E, Camacho CJ, Bernstein KA, Colaiacovo MP, Yanowitz JL.   +10 more
europepmc   +1 more source

BARD1: A Friend or Foe in Pancreatic Ductal Adenocarcinoma? [PDF]

Int J Mol Sci
Zekavat L, Jain A.
europepmc   +1 more source

Exploiting synthetic lethality in epithelial ovarian cancer: multi-dimensional approaches beyond DNA damage repair. [PDF]

Mol Cancer
Bigdeli M, Tremblay E, Provencher D, Mes-Masson AM, Rodier F.   +4 more
europepmc   +1 more source

Deltex and RING-UIM E3 ligases cooperate to create a ubiquitin-ADP-ribose hybrid mark on tankyrase, promoting its stabilization. [PDF]

Sci Adv
Perrard J, Gao K, Ring K, Smith S.
europepmc   +1 more source

Genome-wide CRISPR-Cas9 screening identifies CLK1 inhibition as a strategy to restore PARP inhibitor sensitivity via ERCC1 isoform switching. [PDF]

Protein Cell
Liu C, Xu F, Wu Y, Li J, Ni M, Xia S, Chen L, Zhao H, Yu M, Zhou Y, Zhang M, Li J, Wu X, Huang Y, Zhu T, Chen X.   +15 more
europepmc   +1 more source

Synergistic Effect of Ubiquitin-Specific Protease 14 and Poly(ADP-Ribose) Glycohydrolase Co-Inhibition in BRCA1-Mutant, Poly(ADP-Ribose) Polymerase Inhibitor-Resistant Triple-Negative Breast Cancer Cells. [PDF]

Onco Targets Ther
Li P, Zhu X, Qu H, Han Z, Yao X, Wei Y, Li B, Chen H.   +7 more
europepmc   +1 more source