Results 141 to 150 of about 3,357,233 (168)

Mono‐galloyl glucose derivatives are potent poly(ADP‐ribose) glycohydrolase (PARG) inhibitors and partially reduce PARP‐1‐dependent cell death

British Journal of Pharmacology, 2008
Laura Formentini, Stefano Menichetti
exaly  

PARG INHIBITORS AND METHOD OF USE THEREOF

2020
YU XIAOCHUN, CHEN SHIH-HSUN, HORNE DAVID, XIE JUN   +3 more
openaire   +2 more sources

Novel cell-permeable PARG inhibitors are selective and sensitize cells to alkylating DNA damage

European Journal of Cancer, 2016
D. James, E. Fairweather, L. Griffiths, G. Hopkins, A. Jordan, A. McGonagle, K. Smith, A. Stowell, I. Waddell, D. Ogilvie   +9 more
openaire   +1 more source

PARG dysfunction enhances DNA double strand break formation in S-phase after alkylation DNA damage and augments different cell death pathways

Cell Death and Disease, 2013
M Masutani
exaly  

358 (PB346): A novel small molecule inhibitor of PARG, YL-18319, promotes tumor regression in BRCAmutated, Homologous Recombination Deficient, and PARP-inhibitor resistant cancer models

European Journal of Cancer
D. Weaver, Y. Lou, R. Wild, M. Johnson, Z. Xu   +4 more
semanticscholar   +1 more source

Two small enzyme isoforms mediate mammalian mitochondrial poly(ADP-ribose) glycohydrolase (PARG) activity

Experimental Cell Research, 2007
Ralph Guenter Meyer, Mirella Meyer-Ficca, Myron K Jacobson   +2 more
exaly  

SMALL MOLECULE PARG INHIBITORS AND METHODS OF USE THEREOF

2020
TAINER JOHN A, AHMED ZAMAL, JONES DARIN E, KIM IN-KWON, ELLENBERGER TOM, HO CHRIS   +5 more
openaire   +2 more sources

4-SUBSTITUTED INDOLE AND INDAZOLE SULFONAMIDO DERIVATIVES AS PARG INHIBITORS

2021
SUTTON JR, DILLON MICHAEL PATRICK
openaire   +1 more source

Abstract 1995: HuR dependent inhibition of PARG enhances PARP inhibitor therapy for DNA repair proficient and deficient pancreatic cancer cells

, 2016
Saswati N Chand, Mahsa Zarei, Akshay R. Kamath, M. Schiewer, C. Romeo, J. Cozzitorto, Nicole C Meisner-Kober, Eric Londin, I. Rigoutsos, K. Knudsen, J. Pascal, C. Yeo, J. Winter, J. Brody   +13 more
semanticscholar   +1 more source

INHIBITORS OF PARG

WIDDOWSON KATHERINE, CHANG PAUL, QIAN XIJUN, WANG YANLI, TAN ENWANG   +4 more
openaire   +3 more sources