Results 221 to 230 of about 9,647,508 (315)

Transplantation of Embryonic Dopamine Neurons for Severe Parkinson's Disease [PDF]

, 2001
Curt R. Freed, Paul Greene, Robert E. Breeze, Wei‐Yann Tsai, William DuMouchel, Richard Kao, Sandra Dillon, Howard N. Winfield, Sharon Culver, John Q. Trojanowski, David Eidelberg, Stanley Fahn   +11 more
openalex   +1 more source

Microvascular Health as a Key Determinant of Organismal Aging

Advanced Science, EarlyView.
This review spotlights the emerging field of vascular aging, providing a comprehensive and critical overview of the molecular processes and clinical manifestations of vascular dysfunction during aging. By combining basic angioscience concepts with a critical analysis of innovative pre‐clinical aging models and lifestyle interventions, it offers a ...
Mattia Cenciarini, Andrea Uccelli, Francesca Mangili, Myriam Grunewald, Simone Bersini   +4 more
wiley   +1 more source

Narrative Review: Gut Microbiota and Its Impact on α-syn Function in Parkinson's Disease. [PDF]

Microbiologyopen
Salinas-Velarde ID, Donaciano-Domínguez JM, Oros-Pantoja R, Aguirre-Garrido JF, González-Cervantes RM, Munguía-Cervantes JE, López MG, Bustos-Martínez J, Soto-Piña AE.   +8 more
europepmc   +1 more source

Prevalence of and indications for antipsychotic use in Parkinson's disease

, 2017
James H. Bower, Brandon R. Grossardt, Walter A. Rocca, Rodolfo Savica   +3 more
openalex   +2 more sources

Non motor subtypes and Parkinson's disease [PDF]

, 2015
Anna Sauerbier, Peter Jenner, Antonia Todorova, К. Ray Chaudhuri   +3 more
openalex   +1 more source

Morphological and Hyperphosphorylation Transitions of Nanoscale Tau Aggregates in Alzheimer's Disease

Advanced Science, EarlyView.
Super‐resolution microscopy identifies nano‐sized tau aggregates (nano‐aggregates) and reveals distinct transitions in their morphology and phosphorylation profiles across control, Primary Age‐Related Tauopathy, and Alzheimer's disease brains. Morphology and hyperphosphorylation signatures distinguish physiological from pathological forms, with nano ...
Adriana N. Santiago‐Ruiz, Siewert Hugelier, Gabriela L. Correa, Charles R. Bond, Edward B. Lee, Melike Lakadamyali   +5 more
wiley   +1 more source

Discriminating α-synuclein strains in Parkinson’s disease and multiple system atrophy

Nature, 2020
M. Shahnawaz, Abhisek Mukherjee, S. Pritzkow, Nicolas Mendez, Prakruti Rabadia, Xiangan Liu, Bo Hu, A. Schmeichel, W. Singer, Gang Wu, A. Tsai, Hamid Shirani, K. Nilsson, Phillip A. Low, C. Soto   +14 more
semanticscholar   +1 more source

Top motor and non-motor complaints in patients with Parkinson's disease. [PDF]

Front Aging Neurosci
Baizabal-Carvallo JF, Alonso-Juarez M, Fekete R.   +2 more
europepmc   +1 more source

Association of PINK1 and DJ-1 confers digenic inheritance of early-onset Parkinson's disease [PDF]

, 2006
Beisha Tang, Hui Xiong, Ping Sun, Yuhu Zhang, Danling Wang, Zhengmao Hu, Zan-Hua Zhu, Hong Ma, Qian Pan, Jiahui Xia, Kun Xia, Zhuohua Zhang   +11 more
openalex   +1 more source

Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3

Advanced Science, EarlyView.
In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang, Linghua Zeng, Kunkun Zou, Keying Lin, Fangting Yao, Jinglun Song, Shumeng Zhang, Hanshu Feng, Zhichao Yang, Chunlei Wang, Hongtao Diao, Xue Kong, Tengfei Pan, Joonki Kim, Tianqi Duo, Linqiang Li, Yu Bian   +16 more
wiley   +1 more source