Results 101 to 110 of about 449,138 (190)

Recent Advances in Understanding and Managing Tourette Syndrome [version 1; referees: 3 approved]

open access: yesF1000Research, 2016
Tourette syndrome (TS) is a neurologic and behavioral disorder consisting of motor and phonic tics with onset in childhood or adolescence. The severity of tics can range from barely perceptible to severely impairing due to social embarrassment ...
Mary Ann Thenganatt, Joseph Jankovic
doaj   +1 more source

MOESM3 of Prevalence and incidence of Parkinsonâ s disease and drug-induced parkinsonism in Korea

open access: yes, 2019
Additional file 3: Figure S2. Sensitivity analysis. Number of incident patients with drug-induced parkinsonism by the types and numbers of offending drugs in ...
Sola Han   +5 more
openaire   +1 more source

Botulinum Toxin for the Treatment of Hand Tremor

open access: yesToxins, 2018
The aim of this study is to review our longitudinal experience with onabotulinumtoxinA (onaBoNT-A) injections for medically refractory hand tremor. We performed a retrospective review of our database of patients treated with onaBoNT-A for hand tremor ...
Nicki Niemann, Joseph Jankovic
doaj   +1 more source

Targeting Alpha-Synuclein as a Therapy for Parkinson’s Disease

open access: yesFrontiers in Molecular Neuroscience, 2019
Parkinson’s disease (PD) is one of the most common neurodegenerative disorders with a global burden of approximately 6.1 million patients. Alpha-synuclein has been linked to both the sporadic and familial forms of the disease.
Carroll Rutherford Fields   +2 more
doaj   +1 more source

MOESM1 of Brain mediators of systemic oxidative stress on perceptual impairments in Parkinsonâ s disease

open access: yes, 2015
Additional file 1. Detail T1-weighted structural MRI image processing procedures.
Wei-Che Lin   +12 more
openaire   +1 more source

Sleep dysfunction and EEG alterations in mice overexpressing alpha-synuclein. [PDF]

open access: yes, 2014
BackgroundSleep disruptions occur early and frequently in Parkinson's disease (PD). PD patients also show a slowing of resting state activity. Alpha-synuclein is causally linked to PD and accumulates in sleep-related brain regions.
Chesselet, Marie-Françoise   +3 more
core  

Angiotensin type 1 receptor activation promotes neuronal and glial alpha-synuclein aggregation and transmission

open access: yesnpj Parkinson's Disease
The brain renin-angiotensin system (RAS) has been related to dopaminergic degeneration, and high expression of the angiotensin II (AngII) type 1 receptor (AT1) gene is a marker of the most vulnerable neurons in humans.
Lucia Lage   +4 more
doaj   +1 more source

Parkinsonisms and Glucocerebrosidase Deficiency: A Comprehensive Review for Molecular and Cellular Mechanism of Glucocerebrosidase Deficiency

open access: yesBrain Sciences, 2019
In the last years, lysosomal storage diseases appear as a bridge of knowledge between rare genetic inborn metabolic disorders and neurodegenerative diseases such as Parkinson’s disease (PD) or frontotemporal dementia. Epidemiological studies helped
Emilia M. Gatto   +4 more
doaj   +1 more source

EoL: Towards Quality Care at the End of Life [PDF]

open access: yes, 2009
Palliative and end-of-life care must be available to all who require it, regardless of location, age, income, diagnosis or prognosis, and social and cultural background.

core  

MOESM3 of A randomized controlled efficacy study of the Medido medication dispenser in Parkinsonâ s disease

open access: yes, 2019
Additional file 3. Table with secondary outcomes of UPDRS-4.
K. Hannink   +8 more
openaire   +1 more source

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