Results 41 to 50 of about 449,138 (190)

Additional file 1: of Cerebellar involvement in Parkinsonâ s disease resting tremor

, 2016
Summary Analysis Data. (DOCX 13 kb)
Lefaivre, Shannon, Brown, Matt, Almeida, Quincy   +2 more
openaire   +1 more source

Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation

npj Parkinson's Disease
Understanding medium spiny neuron (MSN) physiology is essential to understand motor impairments in Parkinson’s disease (PD) given the architecture of the basal ganglia.
Quyen B. Do, Humaira Noor, Ricardo Marquez-Gomez, Kaitlyn M. L. Cramb, Bryan Ng, Ajantha Abbey, Naroa Ibarra-Aizpurua, Maria Claudia Caiazza, Parnaz Sharifi, Charmaine Lang, Dayne Beccano-Kelly, Jimena Baleriola, Nora Bengoa-Vergniory, Richard Wade-Martins   +13 more
doaj   +1 more source

Axonal Modulation of Striatal Dopamine Release by Local γ-Aminobutyric Acid (GABA) Signalling

Cells, 2021
Striatal dopamine (DA) release is critical for motivated actions and reinforcement learning, and is locally influenced at the level of DA axons by other striatal neurotransmitters. Here, we review a wealth of historical and more recently refined evidence
Bradley M. Roberts, Emanuel F. Lopes, Stephanie J. Cragg   +2 more
doaj   +1 more source

The Physiology and Psychology of Exercise and Parkinson\u27s Disease [PDF]

, 2015
Parkinson’s disease is one of the most common degenerative neurological disorders and is currently lacking a cure. While physicians have long debated over the best treatment for Parkinson’s symptoms, treatments such as oral medication and deep brain ...
Gibson, Jess
core   +1 more source

S100B is increased in Parkinson’s disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway [PDF]

, 2012
Peer reviewedPublisher ...
Berg, Daniela, Fleckenstein, Corinna, Itohara, Shigeyoshi, Lang, Johannes, Maetzler, Walter, Martin, Heather Louise, Mounsey, Ross Brian, Mustafa, Sarah, Sathe, Kinnari, Schulte, Claudia, Synofzik, Matthis, Teismann, Peter, Vukovic, Zvonimir   +12 more
core   +1 more source

Parkinson’s Disease Quality of Life: Disease Severity Outweighs Pain Impact

Jurnal Kesehatan Prima
Introduction: Parkinson's disease is the second most common neurodegenerative disorder after Alzheimer's disease, progressively affecting both motor and non-motor systems in patients. In addition to the commonly recognized motor symptoms such as tremor, rigidity, and bradykinesia, non-motor symptoms such as chronic pain are often underdiagnosed.
Neila Raisa, Yulianda Maziya, Annisa Rahma, Novita Titis Harbiyanti, Shahdevi Nandar Kurniawan   +4 more
openaire   +1 more source

MOESM2 of White matter damage and systemic inflammation in Parkinsonâ s disease

, 2017
Additional file 2: Partial correlation between DTI indices and clinical disease severity.
Pi-Ling Chiang, Hsiu-Ling Chen, Cheng-Hsien Lu, Pei-Chin Chen, Meng-Hsiang Chen, I.-Hsiao Yang, Nai-Wen Tsai, Wei-Che Lin   +7 more
openaire   +1 more source

Incidence of mild cognitive impairment and dementia in Parkinson's disease: The Parkinson's disease cognitive impairment study [PDF]

, 2019
Background: Cognitive impairment in Parkinson's disease (PD) includes a spectrum varying from Mild Cognitive Impairment (PD-MCI) to PD Dementia (PDD). The main aim of the present study is to evaluate the incidence of PD-MCI, its rate of progression to ...
Baschi R., Cicero C. E., Davi M., Luca A., Monastero R., Mostile G., Nicoletti A., Pilati L., Restivo V., Zappia M.   +9 more
core   +1 more source

MOESM1 of White matter damage and systemic inflammation in Parkinsonâ s disease

, 2017
Additional file 1: Supplementary methods of DTI data preprocessing and analysis.
Pi-Ling Chiang, Hsiu-Ling Chen, Cheng-Hsien Lu, Pei-Chin Chen, Meng-Hsiang Chen, I.-Hsiao Yang, Nai-Wen Tsai, Wei-Che Lin   +7 more
openaire   +1 more source

Dopamine D2 receptor upregulation in dorsal striatum in the LRRK2-R1441C rat model of early Parkinson’s disease revealed by in vivo PET imaging

Scientific Reports
We conducted PET imaging with [18F]FDOPA and dopamine D2/3 receptor ligand [18F]fallypride in aged transgenic rats carrying human pathogenic LRRK2 R1441C or G2019S mutations.
Teresa Delgado-Goñi, Natalie Connor-Robson, Milena Cioroch, Stephen Paisey, Christopher Marshall, Emma L. Lane, David Hauton, James McCullagh, Peter J. Magill, Stephanie J. Cragg, Clare E. Mackay, Richard Wade-Martins, Johannes C. Klein   +12 more
doaj   +1 more source