Results 41 to 50 of about 9,678,735 (383)

Factors affecting mortality in late stage Parkinson’s Disease [PDF]

, 2019
To determine the effect of dysphagia and hospital admissions on mortality in late stage Parkinson’s ...
Dempsey, S., Gray, William Keith, Hand, Annette, McDonald, L., Sayers, I., Walker, Richard   +5 more
core   +1 more source

Structural MRI Correlates of Episodic Memory Processes in Parkinson's Disease Without Mild Cognitive Impairment. [PDF]

, 2015
BackgroundChanges in episodic memory are common early in Parkinson's disease (PD) and may be a risk factor for future cognitive decline. Although medial temporal lobe (MTL) memory and frontostriatal (FS) executive systems are thought to play different ...
Filoteo, J Vincent, Harrington, Deborah L, Litvan, Irene, Pirogovsky-Turk, Eva   +3 more
core   +2 more sources

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source

Early deficits in an in vitro striatal microcircuit model carrying the Parkinson’s GBA-N370S mutation

npj Parkinson's Disease
Understanding medium spiny neuron (MSN) physiology is essential to understand motor impairments in Parkinson’s disease (PD) given the architecture of the basal ganglia.
Quyen B. Do, Humaira Noor, Ricardo Marquez-Gomez, Kaitlyn M. L. Cramb, Bryan Ng, Ajantha Abbey, Naroa Ibarra-Aizpurua, Maria Claudia Caiazza, Parnaz Sharifi, Charmaine Lang, Dayne Beccano-Kelly, Jimena Baleriola, Nora Bengoa-Vergniory, Richard Wade-Martins   +13 more
doaj   +1 more source

Essential Tremor and Parkinson’s Disease: Exploring the Relationship

Tremor and Other Hyperkinetic Movements, 2019
Background: There is longstanding controversy surrounding the possible link between essential tremor (ET) and Parkinson’s disease (PD). Inconsistent and unreliable diagnostic criteria may in part account for some of the difficulties in defining the ...
Arjun Tarakad, Joseph Jankovic
doaj   +1 more source

Additional file 1: of Cerebellar involvement in Parkinsonâ s disease resting tremor

, 2016
Summary Analysis Data. (DOCX 13 kb)
Lefaivre, Shannon, Brown, Matt, Almeida, Quincy   +2 more
openaire   +1 more source

S100B is increased in Parkinson’s disease and ablation protects against MPTP-induced toxicity through the RAGE and TNF-α pathway [PDF]

, 2012
Peer reviewedPublisher ...
Berg, Daniela, Fleckenstein, Corinna, Itohara, Shigeyoshi, Lang, Johannes, Maetzler, Walter, Martin, Heather Louise, Mounsey, Ross Brian, Mustafa, Sarah, Sathe, Kinnari, Schulte, Claudia, Synofzik, Matthis, Teismann, Peter, Vukovic, Zvonimir   +12 more
core   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Dopamine D2 receptor upregulation in dorsal striatum in the LRRK2-R1441C rat model of early Parkinson’s disease revealed by in vivo PET imaging

Scientific Reports
We conducted PET imaging with [18F]FDOPA and dopamine D2/3 receptor ligand [18F]fallypride in aged transgenic rats carrying human pathogenic LRRK2 R1441C or G2019S mutations.
Teresa Delgado-Goñi, Natalie Connor-Robson, Milena Cioroch, Stephen Paisey, Christopher Marshall, Emma L. Lane, David Hauton, James McCullagh, Peter J. Magill, Stephanie J. Cragg, Clare E. Mackay, Richard Wade-Martins, Johannes C. Klein   +12 more
doaj   +1 more source

Live Imaging of Axonal Transport in the Motor Neurons of Drosophila Larvae

Bio-Protocol, 2017
Axonal transport, which is composed of microtubules, motor proteins and a variety of types of cargo, is a prominent feature of neurons. Monitoring these molecular dynamics is important to understand the biological processes of neurons as well as ...
Tsuyoshi Inoshita, Nobutaka Hattori, Yuzuru Imai   +2 more
doaj   +1 more source