Results 51 to 60 of about 9,678,735 (383)
Axonal Modulation of Striatal Dopamine Release by Local γ-Aminobutyric Acid (GABA) Signalling
Cells, 2021 Striatal dopamine (DA) release is critical for motivated actions and reinforcement learning, and is locally influenced at the level of DA axons by other striatal neurotransmitters. Here, we review a wealth of historical and more recently refined evidence
Bradley M. Roberts +2 more
doaj +1 more source
MOESM2 of Prevalence and incidence of Parkinsonâ s disease and drug-induced parkinsonism in Korea
, 2019 Additional file 2: Figure S1. Sensitivity analysis. Incidence of drug-induced parkinsonism in Korea.
Sola Han +5 more
openaire +1 more source
Parkinson’s disease: etiopathogenesis and treatment
Journal of Neurology Neurosurgery & Psychiatry, 2020 The concept of ‘idiopathic’ Parkinson’s disease (PD) as a single entity has been challenged with the identification of several clinical subtypes, pathogenic genes and putative causative environmental agents.
J. Jankovic, E. Tan
semanticscholar +1 more source
The Physiology and Psychology of Exercise and Parkinson\u27s Disease [PDF]
, 2015 Parkinson’s disease is one of the most common degenerative neurological disorders and is currently lacking a cure. While physicians have long debated over the best treatment for Parkinson’s symptoms, treatments such as oral medication and deep brain ...
Gibson, Jess
core +1 more source
CCT4 promotes tunneling nanotube formation
FEBS Letters, EarlyView.Tunneling nanotubes (TNTs) are membranous tunnel‐like structures that transport molecules and organelles between cells. They vary in thickness, and thick nanotubes often contain microtubules in addition to actin fibers. We found that cells expressing monomeric CCT4 generate many thick TNTs with tubulin.
Miyu Enomoto +3 more
wiley +1 more source
Brain-derived and in vitro-seeded alpha-synuclein fibrils exhibit distinct biophysical profiles
eLifeThe alpha-synuclein (αSyn) seeding amplification assay (SAA) that allows the generation of disease-specific in vitro seeded fibrils (SAA fibrils) is used as a research tool to study the connection between the structure of αSyn fibrils, cellular seeding ...
Selene Seoyun Lee +2 more
doaj +1 more source
, 2019 Additional file 4. Table with secondary outcomes of PDQ-carer.
K. Hannink +8 more
openaire +1 more source
On the analysis of EEG power, frequency and asymmetry in Parkinson's disease during emotion processing [PDF]
, 2014 Objective: While Parkinson’s disease (PD) has traditionally been described as a movement disorder, there is growing evidence of disruption in emotion information processing associated with the disease.
Ibrahim, Norlinah Mohamed +8 more
core +2 more sources
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Additional file 1: of LRRK2 contributes to monocyte dysregulation in Parkinsonâ s disease
, 2019 Supplementary materials and methods. (PDF 1185 kb)
Bliederhaeuser, Corinna +11 more
openaire +1 more source