Results 111 to 120 of about 68,677 (270)
Clinical features of Parkinson’s disease.
, 2023 Clinical features of Parkinson’s as a proportion by diagnosis of Parkinson’s disease. X-axis: proportion of feature within diagnosis. Abbreviations: Parkinson’s disease (PD), Parkinson’s dementia syndrome (PDD/DLB) and atypical parkinsonian syndrome (APS)
J. Robert Sneyd (16715450) +13 more
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Advanced Science, EarlyView.An orthogonal ionic‐liquid extraction (Orth‐iEA) enables selective isolation of amyloid fibrils. TMGBF4 disrupts hydrogen‐bonded β‐sheet networks to solubilize amyloid aggregates, whereas C12ImCl interacts with hydrophobic regions of non‐amyloid proteins.
Shiying Zheng +10 more
wiley +1 more source
Mean Expression of the X-Chromosome is Associated with Neuronal Density. [PDF]
, 2012 peer reviewedBackground: Neurodegenerative diseases are characterized by key features such as loss of neurons, astrocytosis, and microglial activation/proliferation. These changes cause differences in the density of cell types between control and disease
Pascal F. Durrenberger +43 more
core +1 more source
Temporal Interference Stimulation Enhances Neural Regeneration
Advanced Science, EarlyView.Temporal interference (TI) stimulation is proposed as a non‐invasive approach to enhance neural regeneration in the deep brain. Theta‐band TI modulation selectively promotes neural progenitor cell differentiation in vitro and augments hippocampal neurogenesis in amouse model of Alzheimer's disease‐like amyloidosis.
Sofia Peressotti +15 more
wiley +1 more source
Journal of Biomedical ScienceBackground Dementia with Lewy bodies shares clinical and pathological features with both Parkinson’s disease and Alzheimer’s disease, but the local biological factors that render specific cortical regions vulnerable to atrophy remain poorly defined.
Aline Delva +15 more
doaj +1 more source
Advanced Science, EarlyView.Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari +3 more
wiley +1 more source
The effects of donepezil in Alzheimer's disease - Results from a multinational trial [PDF]
, 1999 Donepezil has been shown to be well tolerated and to improve cognition and global function in patients with mild to moderately severe Alzheimer's disease (AD).
Hecker, J. +7 more
core +1 more source
Impact of Ethnicity on Non-Motor Symptoms of Parkinson's Disease
Journal of Parkinson’s Disease, 2012 Parkinson's disease (PD) is a neurodegenerative illness characterized by various non-motor symptoms that may contribute to disability, impaired quality of life and shortened life expectancy.
Abdul Qayyum Rana +6 more
doaj +1 more source
Advanced Science, EarlyView.This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong +6 more
wiley +1 more source
Can neuroimaging predict dementia in Parkinson’s disease? [PDF]
, 2018 Dementia in Parkinson’s disease affects 50% of patients within 10 years of diagnosis but there is wide variation in severity and timing. Thus, robust neuroimaging prediction of cognitive involvement in Parkinson’s disease is important: (i) to identify at-
Acosta-Cabronero, J +6 more
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