Results 91 to 100 of about 68,677 (270)

Predicting dementia in people with Parkinson’s disease [PDF]

Parkinson’s disease (PD) exhibits a variety of symptoms, with approximately 25% of patients experiencing mild cognitive impairment and 45% developing dementia within ten years of diagnosis.
Tom Hähnel, Hähnel, Tom, Jochen Klucken, Mohamed Aborageh, Aborageh, Mohamed, Martins Conde, Patricia, Holger Fröhlich, Patricia Martins Conde, Klucken, Jochen, Fröhlich, Holger   +9 more
core   +1 more source

Microstate connectivity alterations in patients with early Alzheimer's disease [PDF]

, 2015
Electroencephalography (EEG) microstates and brain network are altered in patients with Alzheimer's disease (AD) and discussed as potential biomarkers for AD. Microstates correspond to defined states of brain activity, and their connectivity patterns may
Andreas Monsch (3564989), Christian Schindler (71594), Stephan RĂźegg (3564995), Michael Ehrensperger (3564992), Nina Benz, Ute Gschwandtner (811880), Monsch, Andreas U., Christian Schindler, Peter Fuhr, Stephan Rüegg, Hardmeier, Martin, Benz, Nina, Rüegg, Stephan, Martin Hardmeier (146865), Michael Ehrensperger, Gschwandtner, Ute, Florian Hatz, Ehrensperger, Michael, Fuhr, Peter, Martin Hardmeier, Andreas U. Monsch, Peter Fuhr (640430), Ute Gschwandtner, Schindler, Christian, Florian Hatz (640427), Nina Benz (3564983), Hatz, Florian   +26 more
core   +1 more source

Can the CERAD neuropsychological battery be used to assess cognitive impairment in Parkinson's disease?

Arquivos de Neuro-Psiquiatria
The Consortium to Establish a Registry for Alzheimer's Disease (CERAD) neuropsychological battery was created to assess cognitive impairment in Alzheimer's disease (AD) but it is widely-used for various dementias. The aim of this study was to analyze the
Carlos Henrique Ferreira Camargo, Augusto Bronzini, Eduardo de Souza Tolentino, Camila Medyk, Gustavo Leopold Schultz-Pereira   +4 more
doaj   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

Moving beyond the pros and cons of automating cognitive testing in pathological aging and dementia: the case for equal opportunity

, 2014
The lack of progress over the last decade in developing treatments for Alzheimer's disease has called into question the quality of the cognitive assessments used while also shifting the emphasis from treatment to prophylaxis by studying the disorder at ...
Wesnes, Keith
core   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

The use of biomarkers for the etiologic diagnosis of MCI in Europe: an EADC survey [PDF]

, 2014
We investigated the use of Alzheimer's disease (AD) biomarkers in European Alzheimer's Disease Consortium centers and assessed their perceived usefulness for the etiologic diagnosis of mild cognitive impairment (MCI).
Erikdotter, M, Samantha Galluzzi, Peters, Oliver, Galluzi, S, Andreas Monsch, Jones, Roy W, Mehrabian, S., Zekry, Dina, Wilcock, G, Sarazin, M., Sánchez-Castellano, Carmen, Martinez-Lage, P, Kehoe, P.G., Wallin, Åsa,, Hallikainen, M., Monsch, A, Santana, I, Felician, O, Frolich, L, Rikkert, M.O., Isabel Santana, Wilcock, Gordon, Jean‐Marc Orgogozo, Flavio Nobili, Mecocci, P, Hausner, Lucrezia, Roy W. Jones, Jessen, F., Heuser, I., Isabell Heuser, Eric Salmon, David Wilkinson, Froelich, L., Félician, Olivier, Maria Eriksdotter, Ceccaldi, M, Sarazin, M, Olde Rikkert, Marcel, de Mendonca, A., Aguera, E., Galluzzi, Samantha, Felician, O., Pasquier, F., Patrick Gavin Kehoe, Wolf, H, Nordberg, Agneta, Shima Mehrabian, Latchezar Traykov, Frolich, L., Mira Didic, Dartigues, Jean François, Hasselbalch, S.G., Aguera, Eduardo, Alberto Lleo, Sarazin, Marie, Martina Bocchetta, Brian Lawlor, Wallin, Åsa K, Dartigues, J.F., Monsch, A., Magda Tsolaki, Wilkinson, D., Giovanni B. Frisoni, Sanchez-Castellano, C, Yener, Goersev, NOBILI, FLAVIO MARIANO, Nobili, Flavio, Eriksdotter, Maria, Bernabei, R, Hallikainen, M, Gertz, H.J., Frisoni, Giovanni B., Lleo, A, Eduardo Aguera, Hallikainen, Merja, Roberto Bernabei, Alexandre de Mendonça, Gordon Wilcock, Visser, Pieter Jelle, Bullock, R., Frisoni, G.B., Bernabei, Roberto, Jones, Roy W., Alexander Kurz, Sanchez-Castellano, C., Wallin, Åsa, Bochetta, M, Bullock, R, Martinez-Lage, P., Patrizia Mecocci, Frank Jessen, Lleo, Alberto, Ceccaldi, M., Pablo Martinez‐Lage, Nobili, F., Florence Pasquier, Salmon, E., Eriksdotter, M., Lawlor, B., de Mendonça, Alexandre, Dartigues, Jean-François, Jessen, F, Pasquier, Florence, Marie Sarazin, Lucrezia Hausner, Monsch, Andreas, Rikkert, Marcel Olde, Dina Zekry, Carmen Sánchez‐Castellano, Pasquier, F, Traykov, L., Didic, M., Tsolaki, M, Nordberg, A., Pieter Jelle Visser, Kehoe, Patrick Gavin, Orgogozo, J.M., Froelich, Lutz, Kurz, A, Nobili, F, Bocchetta, M., Lund University., Martinez-Lage, Pablo, Agneta Nordberg, Åsa K. Wallin, Frisoni, G. B., Hasselbalch, Steen G, Zekry, D., Wilkinson, D, Gertz, Hermann Josef, Ceccaldi, Mathieu, Galluzzi, S., Santana, Isabel, Wilcock, G., Lleo, A., Mehrabian, S, Kurz, A., Heuser, Isabell, Gertz, Hermann-Josef, Kurz, Alexander, Wilkinson, David, Jean‐François Dartigues, Oliver Peters, Hausner, L, Mecocci, Patrizia, Peters, O., Roger Bullock, Lutz Frölich, Frisoni, Giovanni B, Merja Hallikainen, Orgogozo, Jean Marc, Jones, R.W., Henrike Wolf, Nordberg, A, Mecocci, P., Olde Rikkert, M, Olivier Félician, Wolf, Henrike, Bullock, Roger, Yener, G, Wallin, Åsa K., Peters, O, Yener, Görsev, Wolf, H., Didic, Mira, Mathieu Ceccaldi, Hausner, L., de Mendonca, A, Lawlor, Brian, Jessen, Frank, Orgogozo, Jean-Marc, Bernabei, R., Marcel Olde Rikkert, Mendonca, A. de, Heuser, I, Mehrabian, Shima, Salmon, Eric, Traykov, L, Visser, P.J., Bocchetta, Martina, Aguera, E, Martinez Lage, Pablo, Frölich, Lutz, Hermann‐Josef Gertz, Steen G. Hasselbalch, Didic, M, Tsolaki, M., Tsolaki, Magda, Hasselbalch, Steen G., Santana, I., Hasselbach, S.G., Lawlor, B, Olde Rikkert, M.G.M., Yener, G., Görsev Yener, Wallin, A.K., Traykov, Latchezar, Sänchez Castellano, Carmen   +197 more
core   +1 more source

High delta and gamma EEG power in resting state characterise dementia in Parkinson’s patients

Biomarkers in Neuropsychiatry, 2020
Background: Parkinson’s disease (PD) is a chronic neurodegenerative disease with appearance of dementia as the disease progresses. Dementia in PD worsens the quality of life and poses a burden on caregivers.
Anita Pal, Nishi Pegwal, Madhuri Behari, Ratna Sharma   +3 more
doaj   +1 more source

Recurrent Hypothermia and Autonomic Dysfunction Secondary to Shapiro Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT A 44‐year‐old man presented with recurrent hypothermia, diaphoresis and hypertension. Extensive investigation for infectious, inflammatory, metabolic and endocrine aetiologies was negative. MR scan of the brain demonstrated no lesions but revealed callosal dysgenesis, consistent with Shapiro syndrome.
Naveen Kumar, Jeremy Johnson, Susanne Watkins, Eoin Mulroy   +3 more
wiley   +1 more source

Differentiation of dementia with Lewy bodies from Alzheimer's disease using a dopaminergic presynaptic ligand

, 2002
Background: Dementia with Lewy bodies (DLB) is one of the main differential diagnoses of Alzheimer's disease (AD). Key pathological features of patients with DLB are not only the presence of cerebral cortical neuronal loss, with Lewy bodies in surviving ...
Livingston, G, Costa, DC, Shaw, K, Ince, P, Gacinovic, S, Walker, RWH, Stevens, T, Katona, CLE, McKeith, IG, Walker, Z   +9 more
core