Parkinson's disease dementia: a neural networks perspective. [PDF]
Brain : a journal of neurology, 2015 In the long-term, with progression of the illness, Parkinson's disease dementia affects up to 90% of patients with Parkinson's disease. With increasing life expectancy in western countries, Parkinson's disease dementia is set to become even more ...
Foltynie, T, Gratwicke, J, Jahanshahi, M
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Blood-brain barrier opening with focused ultrasound in Parkinson's disease dementia. [PDF]
Nat Commun, 2021 MR-guided focused ultrasound (MRgFUS), in combination with intravenous microbubble administration, has been applied for focal temporary BBB opening in patients with neurodegenerative disorders and brain tumors.
Gasca-Salas C +14 more
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Neuroinflammation and protein pathology in Parkinson's disease dementia. [PDF]
Acta Neuropathol Commun, 2020 Parkinson’s disease dementia is neuropathologically characterized by aggregates of α-synuclein (Lewy bodies) in limbic and neocortical areas of the brain with additional involvement of Alzheimer’s disease-type pathology.
Kouli A +3 more
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Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders. [PDF]
Cell Res, 2022 Dear Editor, Protein amyloid aggregation is a histological hallmark of neurodegenerative diseases (NDs). 1,2 In synucleinopathies includ-ing Parkinson ’ s disease (PD), Parkinson ’ s disease dementia (PDD), dementia with Lewy body and multiple system ...
Fan Y +16 more
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Neuroimaging in Parkinson's disease dementia: connecting the dots. [PDF]
Brain Commun, 2019 Heterogeneous neuroimaging findings in Parkinson’s dementia localise to a common brain network centred on the hippocampus. This result is symptom and disease-stage specific, as visual hallucinations and mild cognitive impairment map to different networks.
Weil RS +4 more
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Are dementia with Lewy bodies and Parkinson’s disease dementia the same disease?
BMC Medicine, 2018 BackgroundDementia with Lewy bodies (DLB) and Parkinson’s disease dementia (PDD), which share many clinical, neurochemical, and morphological features, have been incorporated into DSM-5 as two separate entities of major neurocognitive disorders with Lewy
K. Jellinger, A. Korczyn
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Incidence of mild cognitive impairment and dementia in Parkinson's disease: The Parkinson's disease cognitive impairment study [PDF]
, 2019 Background: Cognitive impairment in Parkinson's disease (PD) includes a spectrum varying from Mild Cognitive Impairment (PD-MCI) to PD Dementia (PDD). The main aim of the present study is to evaluate the incidence of PD-MCI, its rate of progression to ...
Baschi R. +9 more
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Structural MRI Correlates of Episodic Memory Processes in Parkinson's Disease Without Mild Cognitive Impairment. [PDF]
, 2015 BackgroundChanges in episodic memory are common early in Parkinson's disease (PD) and may be a risk factor for future cognitive decline. Although medial temporal lobe (MTL) memory and frontostriatal (FS) executive systems are thought to play different ...
Filoteo, J Vincent +3 more
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Environmental Health, 2020 Background Emerging evidence links road proximity and air pollution with cognitive impairment. Joint effects of noise and greenness have not been evaluated.
Weiran Yuchi +4 more
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Survival and years of life lost in various aetiologies of dementia, mild cognitive impairment (MCI) and subjective cognitive decline (SCD) in Norway. [PDF]
PLoS ONE, 2018 INTRODUCTION:Alzheimer's disease patients are reported to have higher survival rate compared to patients with vascular dementia or dementia with Lewy bodies.
Bjørn Heine Strand +8 more
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