Results 101 to 110 of about 441,310 (305)

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown   +6 more
wiley   +1 more source

Current update on the protective effect of epicatechin in neurodegenerative diseases

open access: yesEXCLI Journal : Experimental and Clinical Sciences, 2022
Riya Thapa   +9 more
doaj   +1 more source

Clinical Validation of Plasma p‐217tau in Neurological Diseases

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi   +13 more
wiley   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao   +7 more
wiley   +1 more source

NAVSTAR: Global positioning system an evolutionary research and development program [PDF]

open access: yes
A description is given of NAVSTAR and the conception validation program for the system.
Parkinson, B. W.
core   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan   +9 more
wiley   +1 more source

Tank Tests of Model 11-G Flying-boat Hull [PDF]

open access: yes
The NACA model 11-G flying-boat hull, a modification of NACA model 11-A was tested over a range of loadings. The planing bottom of model 11-G has a variable-radius flare, or concavity, at the chines in contrast to the straight V planing bottom of model ...
Parkinson, J B
core   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao   +6 more
wiley   +1 more source

Effectiveness of the mindfulness therapy on the life quality and psychological wellbeing of parkinson patients

open access: yesمجله علوم روانشناختی, 2020
Background: The emergence of chronic diseases such as Parkinson seriously damages the patients’ Life Quality and Psychological Wellbeing besides physical health.
Mina Moghtaderi   +4 more
doaj  

Sea ice/climate studies [PDF]

open access: yes
The objectives were to determine and analyze the annual cycle of sea ice extents in the Arctic Ocean and peripheral seas and bays over the period 1973 to 1986, looking in particular for any long term trends; to examine the relationship between local sea ...
Parkinson, C. L.
core   +1 more source

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