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BackgroundAlthough bedrooms are identified as a major location for accidents among Parkinson’s disease (PD) patients, there are no studies that specifically evaluate the bedroom environments of PD patients.ObjectiveTo examine the physical bedroom ...
Roongroj Bhidayasiri+11 more
doaj +1 more source
A smart tool for the diagnosis of Parkinsonian syndrome using wireless watches [PDF]
This work is licensed under a Creative Commons Attribution 3.0 License.Early detection and diagnosis of Parkinson disease will provide a good chance for patients to take early actions and prevent its further development.
Goll, A, Meng, H
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Balance dysfunction (BD) in Parkinson’s disease (PD) is a disabling symptom, difficult to treat and predisposing to falls. The dopaminergic drugs or deep brain stimulation does not always provide significant improvements of BD and rehabilitative ...
Davide Ferrazzoli+7 more
doaj +1 more source
How to spot ocular abnormalities in progressive supranuclear palsy? A practical review
Background For parkinsonian disorders, progressive supranuclear palsy (PSP) continues to be significant for differential diagnosis. PSP presents a range of ocular abnormalities that have been suggested as optional tools for its early detection, apart ...
Onanong Phokaewvarangkul+1 more
doaj +1 more source
Recent developments in biomarkers in Parkinson disease. [PDF]
Parkinson disease is the second most common neurodegenerative disease after Alzheimer disease, and current demographic trends indicate a life-time risk approaching 4% and predict a doubling of prevalence by 2030.
Schapira, AH
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Methamphetamine and Parkinson's Disease [PDF]
Parkinson's disease (PD) is a neurodegenerative disorder predominantly affecting the elderly. The aetiology of the disease is not known, but age and environmental factors play an important role. Although more than a dozen gene mutations associated with familial forms of Parkinson's disease have been described, fewer than 10% of all cases can be ...
Rosario Moratalla+6 more
openaire +5 more sources
Parkinson’s disease: etiopathogenesis and treatment
The concept of ‘idiopathic’ Parkinson’s disease (PD) as a single entity has been challenged with the identification of several clinical subtypes, pathogenic genes and putative causative environmental agents.
J. Jankovic, E. Tan
semanticscholar +1 more source
Noradrenaline and Parkinson's Disease [PDF]
Parkinson's disease (PD) is characterized by the degeneration of dopamine (DA) neurons in the substantia nigra pars compacta, and motor symptoms including bradykinesia, rigidity, and tremor at rest. These symptoms are exhibited when striatal dopamine concentration has decreased by around 70%.
Claire eDelaville+3 more
openaire +5 more sources
Onset of Mild Cognitive Impairment in Parkinson Disease [PDF]
Objective: Characterize the onset and timing of cognitive decline in Parkinson disease (PD) from the first recognizable stage of cognitively symptomatic PD-mild cognitive impairment (PD-MCI) to PD dementia (PDD).
Barton+34 more
core +2 more sources
DJ-1 isoforms in whole blood as potential biomarkers of Parkinson disease [PDF]
DJ-1 is a multifunctional protein that plays an important role in oxidative stress, cell death, and synucleinopathies, including Parkinson disease. Previous studies have demonstrated that total DJ-1 levels decrease in the cerebrospinal fluid, but do not ...
Cain, Kevin C+14 more
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