Results 31 to 40 of about 119,702 (338)
There Is No Parkinson Disease [PDF]
Archives of Neurology, 2008 The term Parkinson disease defines a specific clinical condition characterized by a typical history and characteristic signs. This review examines the historical evolution of the concept of Parkinson disease and how the misunderstanding of Parkinson disease may be hindering clinical research trials. It is proposed that this syndrome be called Parkinson
openaire +3 more sources
Analysis and Evaluation of Handwriting in Patients with Parkinson's Disease Using kinematic, Geometrical, and Non-linear Features [PDF]
Computer methods and programs in biomedicine, 173, 43-52 (2019), 2020 Background and objectives: Parkinson's disease is a neurological disorder that affects the motor system producing lack of coordination, resting tremor, and rigidity. Impairments in handwriting are among the main symptoms of the disease. Handwriting analysis can help in supporting the diagnosis and in monitoring the progress of the disease.
arxiv +1 more source
Brain Sciences, 2023 Objective: To investigate whether impaired plantar cutaneous vibration perception contributes to axial motor symptoms in Parkinson’s disease (PD) and whether anti-parkinsonian medication and subthalamic nucleus deep brain stimulation (STN-DBS) show ...
Tobias Heß +3 more
doaj +1 more source
Rehabilitation and Parkinson’s Disease [PDF]
Parkinson's Disease, 2012 Early after the turn of the century, much excitement was generated by the reports of Tillerson et al. [1, 2] that exercise appeared to protect against neuronal degeneration in rodent models of toxin-induced parkinsonism. Such findings, coupled with epidemiologic suggestions that persons with a history of moderate to vigorous exercise may have a ...
Gammon M. Earhart +3 more
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Are the digit ratio (2D:4D) and hand grip strength related to Parkinson disease in elderly males?
BMC Sports Science, Medicine and Rehabilitation, 2023 Background Sex hormones affect the pathogenesis of Parkinson patients and it has been suggested that gender is the most important factor in the development and progression of Parkinson’s disease.
Hamid Arazi +2 more
doaj +1 more source
Visual exploration in Parkinson’s disease and Parkinson’s disease dementia [PDF]
Brain, 2013 Parkinson's disease, typically thought of as a movement disorder, is increasingly recognized as causing cognitive impairment and dementia. Eye movement abnormalities are also described, including impairment of rapid eye movements (saccades) and the fixations interspersed between them.
Michael P. Clarke +5 more
openaire +5 more sources
Molecular Oncology, EarlyView.Patient engagement involves actively including patients in healthcare decisions and research to ensure care and studies align with their needs. This approach improves outcomes, trust, and communication while fostering collaboration between patients and professionals.
Estela Cepeda +3 more
wiley +1 more source
Measuring the Burden of Hospitalization in Patients with Parkinson´s Disease in Spain.
PLoS ONE, 2016 IntroductionThis epidemiological survey estimates the hospitalization burden related to Parkinson´s Disease in Spain.MethodsThis observational retrospective survey was performed by reviewing data from the National Surveillance System for Hospital Data ...
Ruth Gil-Prieto +5 more
doaj +1 more source
Mapping Hsp104 interactions using cross‐linking mass spectrometry
FEBS Open Bio, EarlyView.This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal +3 more
wiley +1 more source
Neuropsychiatric symptoms and cognitive abilities over the initial quinquennium of Parkinson disease
Annals of Clinical and Translational Neurology, 2020 Objective To determine the evolution of numerous neuropsychiatric symptoms and cognitive abilities in Parkinson disease from disease onset. Methods Prospectively collected, longitudinal (untreated, disease onset to year 5), observational data from ...
Daniel Weintraub +19 more
doaj +1 more source