Results 41 to 50 of about 5,373,856 (290)

Condições de saúde dos idosos com doença de Parkinson [PDF]

, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2015.Trata-se de uma pesquisa de abordagem quantitativa e de corte transversal, com análise descritiva e
Baptista, Rafaela
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Risk of Parkinson Disease and Secondary Parkinsonism in Myocardial Infarction Survivors

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background In addition to primary neurodegenerative processes, vascular disorders, such as stroke, can lead to parkinsonism. However, some cardiovascular risk factors, such as smoking and elevated cholesterol levels, are associated with reduced risk of ...
Jens Sundbøll, Szimonetta Komjáthiné Szépligeti, Péter Szentkúti, Kasper Adelborg, Erzsébet Horváth‐Puhó, Lars Pedersen, Victor W. Henderson, Henrik Toft Sørensen   +7 more
doaj   +1 more source

Associação entre os níveis séricos de neopterina e a doença de Parkinson [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde. Programa de Pós-Graduação em Ciências MédicasJustificativa: Evidências apontam para o envolvimento do sistema imune e neuroinflamação na gênese e progressão da ...
Freitas, Fernando Cini
core  

High intensity training in Parkinson Disease: a look at perception before the function

, 2023
openCome si può intuire dal titolo “Allenamento ad alta intensità nei pazienti con malattia di Parkinson: uno sguardo alla percezione prima che alla funzione”, lo scopo di questo progetto è stato valutare l’effetto che l’allenamento su treadmill ad ...
POLESE, NIKE MARIA
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Parkinson's disease [PDF]

Human Molecular Genetics, 2007
Parkinson's disease (PD) is a chronic progressive neurodegenerative movement disorder characterized by a profound and selective loss of nigrostriatal dopaminergic neurons. Clinical manifestations of this complex disease include motor impairments involving resting tremor, bradykinesia, postural instability, gait difficulty and rigidity.
Bobby, Thomas, M Flint, Beal
openaire   +5 more sources

Microglia depletion reduces neurodegeneration and remodels extracellular matrix in a mouse Parkinson’s disease model triggered by α-synuclein overexpression

npj Parkinson's Disease
Chronic neuroinflammation with sustained microglial activation occurs in Parkinson’s disease (PD), yet the mechanisms and exact contribution of these cells to the neurodegeneration remains poorly understood.
Zhen Zhang, Kun Niu, Taoying Huang, Jiali Guo, Gongbikai Xarbat, Xiaoli Gong, Yunke Gao, Feiyang Liu, Shan Cheng, Wenting Su, Fei Yang, Zhaoyuan Liu, Florent Ginhoux, Ting Zhang   +13 more
doaj   +1 more source

Are the digit ratio (2D:4D) and hand grip strength related to Parkinson disease in elderly males?

BMC Sports Science, Medicine and Rehabilitation, 2023
Background Sex hormones affect the pathogenesis of Parkinson patients and it has been suggested that gender is the most important factor in the development and progression of Parkinson’s disease.
Hamid Arazi, Roghayeh Bavafa Birak Olia, Ehsan Eghbali   +2 more
doaj   +1 more source

Diabetes mellitus and Parkinson disease

, 2018
To investigate whether diabetes mellitus is associated with Parkinson-like pathology in people without Parkinson disease and to evaluate the effect of diabetes mellitus on markers of Parkinson pathology and clinical progression in drug-naive patients ...
Niccolini, Flavia, Heather Wilson, Ferrara, Nicola, Beniamino Giordano, Nicola Ferrara, Flavia Niccolini, Marios Politis, Politis, Marios, Sotirios Polychronis, GIORDANO, BENIAMINO, Polychronis, Sotirios, Wilson, Heather; id_orcid, Pagano, Gennaro, Gennaro Pagano, Wilson, Heather   +14 more
core   +1 more source