Results 61 to 70 of about 262,938 (292)

Handwriting analysis for diagnosis and prognosis of Parkinson’s disease [PDF]

, 2010
At present, there are no quantitative, objective methods for diagnosing the Parkinson disease. Existing methods of quantitative analysis by myograms suffer by inaccuracy and patient strain; electronic tablet analysis is limited to the visible drawing ...
Brause, Rüdiger W., Krakow, Karsten, Ünlü, Atilla   +2 more
core  

Parkinson's disease biomarkers: perspective from the NINDS Parkinson's Disease Biomarkers Program [PDF]

, 2017
Biomarkers for Parkinson's disease (PD) diagnosis, prognostication and clinical trial cohort selection are an urgent need. While many promising markers have been discovered through the National Institute of Neurological Disorders and Stroke Parkinson's ...
Albin, Roger, Alcalay, Roy N., Babcock, Debra, Bowman, F. DuBois, Chen-Plotkin, Alice, David, Karen K., Dawson, Ted M., Dewey, Richard B., Jr., Foroud, Tatiana, German, Dwight, Gwinn, Katrina, Huang, Xuemei, Lungu, Codrin, Petyuk, Vlad, Potashkin, Judith A., Rosenthal, Liana S., Saunders-Pullman, Rachel, Scherzer, Clemens R., Sieber, Beth-Anne, St Hillaire-Clarke, Coryse, Sutherland, Margaret, Swanson-Fischer, Christine, Vaillancourt, David E., Walt, David R., West, Andrew B., Zhang, Jing   +25 more
core   +1 more source

Neuropsychiatric symptoms and cognitive abilities over the initial quinquennium of Parkinson disease

Annals of Clinical and Translational Neurology, 2020
Objective To determine the evolution of numerous neuropsychiatric symptoms and cognitive abilities in Parkinson disease from disease onset. Methods Prospectively collected, longitudinal (untreated, disease onset to year 5), observational data from ...
Daniel Weintraub, Chelsea Caspell‐Garcia, Tanya Simuni, Hyunkeun R. Cho, Christopher S. Coffey, Dag Aarsland, Roy N. Alcalay, Matthew J. Barrett, Lana M. Chahine, Jamie Eberling, Alberto J. Espay, Jamie Hamilton, Keith A. Hawkins, James Leverenz, Irene Litvan, Irene Richard, Liana S. Rosenthal, Andrew Siderowf, Michele York, Parkinson’s Progression Markers Initiative   +19 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Linear modeling of possible mechanisms for parkinson tremor generation [PDF]

, 1978
The power of Parkinson tremor is expressed in terms of possibly changed frequency response functions between relevant variables in the neuromuscular system.
A. N. Lieberman, C. H. Lücking, C. J. Andrews, D. L. McLellan, E. I. Kandel, F. M. R. Walshe, G. M. Jenkins, J. Andrew, J. Holsheimer, J. J. Ackmann, J. M. Gybels, J. Manen van, J. W. Lance, J. W. Magladery, K.-E. Hagbarth, L. D. Partridge, L. J. Pollock, L. Stark, P. Andersen, P. B. C. Matthews, P. Dietrichson, Peter Löhnberg, R. B. Stein, R. E. Sica, R. N. Stiles, R. W. Angel, W. G. Tatton, W. J. Freeman, W. W. Alberts   +28 more
core   +4 more sources

The role of the brain renin-angiotensin system in Parkinson´s disease

Translational Neurodegeneration
The renin-angiotensin system (RAS) was classically considered a circulating hormonal system that regulates blood pressure. However, different tissues and organs, including the brain, have a local paracrine RAS.
Jose Luis Labandeira-Garcia, Carmen M. Labandeira, Maria J. Guerra, Ana I. Rodriguez-Perez   +3 more
doaj   +1 more source

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

The Value of Multidisciplinary Care in Parkinson\u27s Disease [PDF]

, 2003
Educational Objectives 1. To recognize the signs and symptoms of Parkinson\u27s disease (PD). 2. To identify key treatment and management strategies for PD. 3.
Baron, Mark, Hirsch, Miriam
core   +1 more source

Randomized controlled trial of a home-based action observation intervention to improve walking in Parkinson disease [PDF]

, 2016
Published in final edited form as: Arch Phys Med Rehabil. 2016 May ; 97(5): 665–673. doi:10.1016/j.apmr.2015.12.029.OBJECTIVE: To examine the feasibility and efficacy of a home-based gait observation intervention for improving walking in Parkinson ...
Cronin-Golomb, Alice, Ellis, Terry D., Jaywant, Abhishek, Lin, Cheng-Chieh, Neargarder, Sandy, Roy, Serge   +5 more
core   +1 more source

Inhibition of Protease-Activated Receptor-2 Activation in Parkinson’s Disease Using 1-Piperidin Propionic Acid

Biomedicines
In Parkinson’s disease, neuroinflammation is a double-edged sword; when inflammation occurs it can have harmful effects, despite its important role in battling infections and healing tissue.
Santina Quarta, Michele Sandre, Mariagrazia Ruvoletto, Marta Campagnolo, Aron Emmi, Alessandra Biasiolo, Patrizia Pontisso, Angelo Antonini   +7 more
doaj   +1 more source