Results 21 to 30 of about 128,160 (300)
How to spot ocular abnormalities in progressive supranuclear palsy? A practical review
Translational Neurodegeneration, 2019 Background For parkinsonian disorders, progressive supranuclear palsy (PSP) continues to be significant for differential diagnosis. PSP presents a range of ocular abnormalities that have been suggested as optional tools for its early detection, apart ...
Onanong Phokaewvarangkul +1 more
doaj +1 more source
Journal of the American Geriatrics Society, 1997 Summary Parkinson's disease is a common disabling disease of old age. The diagnosis of idiopathic Parkinson's disease is based on clinical signs and has poor sensitivity, with about 25% of patients confidently diagnosed as having the disease actually having other conditions such as multi-system atrophy and other parkinsonism-plus ...
openaire +4 more sources
Small Molecule Chaperones for the Treatment of Gaucher Disease and GBA1-Associated Parkinson Disease
Frontiers in Cell and Developmental Biology, 2020 Parkinson disease, the second most common movement disorder, is a complex neurodegenerative disorder hallmarked by the accumulation of alpha-synuclein, a neural-specific small protein associated with neuronal synapses. Mutations in the glucocerebrosidase
Tae-Un Han, Richard Sam, Ellen Sidransky
doaj +1 more source
, 2023 reservedParkinson disease has different kinds of pathological features,one hallamark is the aggregation of α-synuclein (aSyn).The motor deficits of the Parkinson disease are associated with the pathology of asyn in the substantia nigra.Although,there are
GKRANIA, VASILIKI
core
Risk of Parkinson Disease and Secondary Parkinsonism in Myocardial Infarction Survivors
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background In addition to primary neurodegenerative processes, vascular disorders, such as stroke, can lead to parkinsonism. However, some cardiovascular risk factors, such as smoking and elevated cholesterol levels, are associated with reduced risk of ...
Jens Sundbøll +7 more
doaj +1 more source
Vivendo com a doença de Parkinson [PDF]
, 2015 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2015.Este estudo teve como objetivo compreender os significados que as pessoas com doença de Parkinson ...
Valcarenghi, Rafaela Vivian
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Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Are the digit ratio (2D:4D) and hand grip strength related to Parkinson disease in elderly males?
BMC Sports Science, Medicine and Rehabilitation, 2023 Background Sex hormones affect the pathogenesis of Parkinson patients and it has been suggested that gender is the most important factor in the development and progression of Parkinson’s disease.
Hamid Arazi +2 more
doaj +1 more source
Condições de saúde dos idosos com doença de Parkinson [PDF]
, 2015 Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Enfermagem, Florianópolis, 2015.Trata-se de uma pesquisa de abordagem quantitativa e de corte transversal, com análise descritiva e
Baptista, Rafaela
core
Primary skin fibroblasts as a model of Parkinson's disease [PDF]
, 2012 Parkinson's disease is the second most frequent neurodegenerative disorder. While most cases occur sporadic mutations in a growing number of genes including Parkin (PARK2) and PINK1 (PARK6) have been associated with the disease.
Morales-Gordo, B. +32 more
core +1 more source