Results 81 to 90 of about 9,346,254 (401)
Parkinson's Disease and Parkinsonism: Neuropathology [PDF]
Cold Spring Harbor Perspectives in Medicine, 2012 Parkinsonism, the clinical term for a disorder with prominent bradykinesia and variable associated extrapyramidal signs and symptoms, is accompanied by degeneration of the nigrostriatal dopaminergic system, with neuronal loss and reactive gliosis in the substantia nigra found at autopsy.
openaire +3 more sources
Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement
Neurobiology of Disease, 2008 The ubiquitin–proteasome system (UPS) and the autophagy-lysosomal pathway (ALP) are the two most important cellular mechanisms for protein degradation.
Tianhong Pan +5 more
doaj
Brazilian Journal of Psychiatry, 2009 OBJECTIVE: To evaluate and compare the frequency and severity of major depression in patients with Parkinson's disease and in individuals older than 60 years without neurological, rheumatological and/or oncological comorbidities.
Beatriz Azevedo dos Anjos Godke Veiga +5 more
doaj +1 more source
PENGARUH KADAR APOLIPOPROTEIN A1 DAN DERAJAT KLINIS TERHADAP FUNGSI KOGNITIF PARKINSON [PDF]
, 2016 Retno Tunjungsari. S501202056. 2016. PENGARUH KADAR PLASMA APOLIPO PROTEIN A1 DAN DERAJAT KLINIS TERHADAP FUNGSI KOGNITIF PARKINSON. Thesis. Supervisor I: Dr. Diah Kurnia Mirawati, dr. Sp. S(K)., II: FX. Soetedjo, dr., Sp. S(K).
TUNJUNGSARI, RETNO
core
, 2015 Background: Globally there are few reports of the impairments, disabilities and medications used in people living with idiopathic Parkinson’s disease. Caregiver characteristics and caregiver burden have seldom been reported.
Campbell, Donald +7 more
core +1 more source
Balance differences in people with Parkinson disease with and without freezing of gait [PDF]
, 2015 Published in final edited form as: Gait Posture. 2015 September ; 42(3): 306–309. doi:10.1016/j.gaitpost.2015.06.007.BACKGROUND: Freezing of gait (FOG) is a relatively common and remarkably disabling impairment associated with Parkinson disease (PD).
Cavanaugh, James T. +7 more
core +1 more source
Phenotyping Healthcare Use 2–3 Decades Before the First Multiple Sclerosis Demyelinating Event
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Phenotype hospital, physician, and emergency department (ED) visits by diagnoses and specialty up to 29 years pre‐multiple sclerosis (MS) onset versus a matched population without MS. Methods We identified people with MS (PwMS) using population‐based administrative data from Ontario, Canada (1991–2020).
Helen Tremlett +8 more
wiley +1 more source
Highly challenging balance program reduces fall rate in Parkinson disease [PDF]
, 2016 Published in final edited form as: J Neurol Phys Ther. 2016 January ; 40(1): 24–30. doi:10.1097/NPT.0000000000000111BACKGROUND AND PURPOSE: There is a paucity of effective treatment options to reduce falls in Parkinson disease (PD).
DeAngelis, Tamara R. +5 more
core +1 more source
Genetic Diversity and Expanded Phenotypes in Dystonia: Insights From Large‐Scale Exome Sequencing
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Dystonia is one of the most prevalent movement disorders, characterized by significant clinical and etiological heterogeneity. Despite considerable heritability (~25%), the etiology in most patients remains elusive. Moreover, understanding correlations between clinical manifestations and genetic variants has become increasingly ...
Mirja Thomsen +47 more
wiley +1 more source
Diagnostic value of the impairment of olfaction in Parkinson's disease. [PDF]
PLoS ONE, 2013 Olfactory impairment is increasingly recognized as an early symptom in the development of Parkinson's disease. Testing olfactory function is a non-invasive method but can be time-consuming which restricts its application in clinical settings and ...
Swaantje Casjens +10 more
doaj +1 more source