Diagnostics and treatment of vascular parkinsonism [PDF]
The article presents clinical syndromic classification of parkinsonism in relation to etiological factors. It also studies epidemiologic and historical aspects of vascular parkinsonism.
V.V. Yudina+2 more
doaj
Differential diagnostic relevance of high resolution magnetic resonance in patients with possible multiple system atrophy (MSA) – a case report [Važnost uporabe magnetne rezonancije visoke rezolucije u dijagnostici moguće multiple sistemske atrofije - prikaz slučaja] [PDF]
Multiple system atrophy (MSA) is sporadic, progressive neurodegenerative disorder characterized clinically by autonomic dysfunction, Parkinsonism (MSA-P), and cerebellar ataxia (MSA-C) in any combination.
Bačić Baronica, Koraljka+3 more
core
Physiotherapy versus placebo or no intervention in Parkinson's disease [PDF]
Background: Despite medical therapies and surgical interventions for Parkinson's disease (PD), patients develop progressive disability. Physiotherapy aims to maximise functional ability and minimise secondary complications through movement rehabilitation
Allen+143 more
core +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
The Differential Diagnosis and Treatment of Atypical Parkinsonism.
BACKGROUND Aside from idiopathic Parkinson syndrome (Parkinson's disease), there are a number of other, so-called atypical parkinsonian syndromes: dementia with Lewy bodies (DLB), multiple system atrophy (MSA), progressive supranuclear palsy (PSP), and ...
J. Levin+4 more
semanticscholar +1 more source
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää+2 more
wiley +1 more source
Tyrosine kinases (TKs) are catalytic enzymes activated by auto-phosphorylation that function by phosphorylating tyrosine residues on downstream substrates.
Max Stevenson+2 more
doaj +1 more source
Clinical and genetic analysis of 29 Brazilian patients with Huntington’s disease-like phenotype [PDF]
Huntington’s disease (HD) is a neurodegenerative disorder characterized by chorea, behavioral disturbances and dementia, caused by a pathological expansion of the CAG trinucleotide in the HTT gene. Several patients have been recognized with the typical
Adrian Danek+38 more
core +3 more sources
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu+17 more
wiley +1 more source
Apparently Ipsilateral Parkinsonism in a Patient with Chronic Subdural Hematoma [PDF]
Symptomatic parkinsonism secondary to ipsilateral lesion is rarely reported. Although the contribution of the contralateral lesions was assumed in some cases, the pathomechanism remains undetermined.
Tae Hwan Roh+4 more
doaj +1 more source