Results 101 to 110 of about 127,921 (347)

Alpha-Synuclein Protofibrils in Cerebrospinal Fluid: A Potential Biomarker for Parkinson's Disease

, 2020
Background: Currently, there is no established biomarker for Parkinson's disease (PD) and easily accessible biomarkers are crucial for developing disease-modifying treatments.
Falting, J., Blennow, Kaj,, Constantinescu, R., Höglund, Kina,, Zetterberg, Henrik,, Soderberg, L., Moller, C., Giorgetti, M., von Euler Chelpin, Marianne,   +8 more
core   +1 more source

Prodromal Lewy Body Disorder Features in REM Sleep Behavior Disorder With Biomarker‐Defined Synucleinopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid eye movement sleep behavior disorder (iRBD) is a prodromal state for Lewy body disorders and exhibits biological heterogeneity that may influence clinical expression and progression. We examined clinical features in individuals with iRBD and biomarker‐defined synucleinopathy.
Daniel Weintraub, Michele K. York, Roseanne Dobkin, Anuprita R. Nair, Ryan Kurth, David‐Erick Lafontant, Chelsea Caspell‐Garcia, Roy N. Alcalay, Ethan G. Brown, Lana M. Chahine, Christopher Coffey, Tatiana Foroud, Douglas Galasko, Karl Kieburtz, Kenneth Marek, Kalpana Merchant, Brit Mollenhauer, Kathleen L. Poston, Andrew Siderowf, Cristina Simonet, Tanya Simuni, Caroline M. Tanner, Thomas F. Tropea, Aleksandar Videnovic, The Parkinson's Progression Markers Initiative   +24 more
wiley   +1 more source

The relationship between visuospatial disorders in Parkinson’s disease and thickness of retina and cortex

Анналы клинической и экспериментальной неврологии, 2017
This paper presents the current data on the mechanisms of formationof visuospatial disorders in Parkinsons disease (PD). Opticalcoherence tomography method was used to study the retina,using the protocols designed to assess the thickness of ...
I. V. Litvinenko, E. V. Boyko, A. N. Kulikov, P. S. Dynin, A. G. Trufanov, D. S. Mal’tsev, A. A. Yurin   +6 more
doaj   +1 more source

Median and Ulnar Neuropathy Assessment in Parkinson's Disease regarding Symptom Severity and Asymmetry

, 2016
Background. While increasing evidence suggests comorbidity of peripheral neuropathy (PNP) and Parkinson's disease (PD), the pathogenesis of PNP in PD is still a debate. The aim of this article is to search the core PD symptoms such as rigidity and tremor
Yardimci, Nilgul and Cemeroglu, Ozlem and Ozturk, Eda and Gurlu, Gulsum and Sahin, Esra and Bozkurt, Saliha and Cengiz, Tugba and Karali, Gulderen and Cakirbay, Hasim and Ilhan, Atilla
core   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

Visualization of dopaminergic midbrain structures in Parkinson’s disease

Анналы клинической и экспериментальной неврологии, 2017
MRI morphometry of the substantia nigra (SN) and the rednucleus was performed in patients with Parkinsons disease (PD)(1 and 3 stage by Hoehn and Yahr) and healthy individuals usingmodes T2 and T2*-WI on magnetic resonance system InitialAchieva 3.0T ...
R. R. Bogdanov, E. I. Manannikova, A. S. Abramenko, T. V. Maratkanova, S. V. Kotov   +4 more
doaj   +1 more source

Left-sided hemihypomimia in Parkinsons disease

, 2011
: Parkinsons disease is known to present and mostly persist as an asymmetrical movement disorder in most cases. The asymmetry is mainly described in motor features such as bradykinesia, rigidity and tremor in upper and lower limbs.
van Ael, Yannick, Cras, Patrick, Mar\ue9chal, Emke, Crosiers, David   +3 more
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Atividade física habitual e desempenho motor de indivíduos com e sem a doença de Parkinson [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Desportos, Programa de Pós-Graduação em Educação Física, Florianópolis, 2011Objetivo: Descrever a atividade física habitual e sua associação com o desempenho motor em indivíduos ...
Guimarães, Alexsander Vieira
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Health and Social Service Access Among Family Caregivers of People with Parkinsons Disease

, 2016
Background: Being a family caregiver for a person with Parkinsons disease (PD) can negatively impact health and wellbeing, but it appears less clear to what extent caregivers health/social service needs are met. Objective: We explored the extent to which
Alvariza, Anette,, Årestedt, Kristofer,, Hagell, Peter,, Claren, Lena,, Lund University., Olsson, Yvonne,, Hagellf, Peter,   +6 more
core   +1 more source

Parkinsons sykdom og seksuell helse [PDF]

, 2020
Bakgrunn: Parkinsons sykdom er en nevrodegenerativ sykdom som kan påvirke forhold som normal seksuell aktivitet avhenger av og føre til nedsatt eller tapt seksualfunksjon.
Heggvoll, Trine, Sivertsen, Elisabeth
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