Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Book Review: Lobbying the European Union: Institutions, Actors and Issues, David Coen and Jeremy Richardson (eds.) [PDF]
The volume “Lobbying the European Union: Institutions, Actors and Issues”, collects 16 articles on interest group politics at EU level, focusing on the main elements of European lobbying – the existing relations between the EU institutions and the ...
Alexandra Pop
doaj
TWIN CITY NATURAL FOOD CO-OPS: THE ROLE OF CUSTOMER PREFERENCES AND CHARACTERISTICS WHEN CHOOSING AMONG STRUCTURAL OPTIONS [PDF]
The demand for natural foods has been growing steadily over the past decade. As more mainstream grocers and investor-owned, natural food chains respond to this increased demand, the viability of local, independent natural food co-ops (TCNFCs) was used to
Mancino, Lisa, Parliament, Claudia
core +1 more source
Structure and evolution of a European Parliament via a network and correlation analysis [PDF]
We present a study of the network of relationships among elected members of the Finnish parliament, based on a quantitative analysis of initiative co-signatures, and its evolution over 16 years.
Pajala, Antti+3 more
core +2 more sources
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
The1997 Scottish referendum : an analysis of the Scottish referendum [PDF]
Referendums are rare events in the United Kingdom. Only one UK-wide referendum has been held - on membership of the European Community (as it then was) in 1975 - and before 1997 there had been only three other significant referendums: in 1973, in ...
Bochel, H.+3 more
core
Learning lessons? The registration of lobbyists at the Scottish parliament: a reply to Coldwell [PDF]
The Scottish Parliament was founded on principles of openness and accessibility and signalled the potential for a new style of politics post devolution.
Dinan, William
core +1 more source
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma+9 more
wiley +1 more source
A Tale of Two Serbias? Census-taking in 2002 and 2011
The challenges implicit in census-taking are especially pronounced in the Western Balkans and, very specifically, in Serbia, considering this country’s multi-ethnic and multi-religious makeup, as reflected in territorial delineations, as well as its ...
Mina Djurić Nikolić, Laura Trimajova
doaj
The macroeconomic consequences of Scottish fiscal autonomy: inverted haavelemo effects in a general equilibrium analysis of the tartan tax [PDF]
In 1997 the Scottish people voted both for the creation of a legislative Parliament and to endow the Parliament with tax-varying powers. The establishment of the Scottish Parliament in 2000 heralded the most radical innovation in the regional fiscal ...
McGregor, Peter G.+2 more
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