Results 51 to 60 of about 15,613 (254)

Treatment of paroxysmal nocturnal hemoglobinuria

Онкогематология, 2014
Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, life‑threatening clonal hematological disorder caused by an acquired mutation in the phosphatidylinositol glucan (PIG)-A gene.
I. A. Lisukov, A. D. Kulagin, B. V. Afanasyev   +2 more
doaj   +3 more sources

Short-term recurrent coronary artery thrombosis with acute myocardial infarction in a patient with aplastic anemia–paroxysmal nocturnal hemoglobinuria syndrome: a case report

Frontiers in Cardiovascular Medicine
BackgroundAcute myocardial infarction commonly occurs in patients with coronary artery disease, but rarely, it can develop under a hypercoagulable state.
Xue-Guo Fu, Yan-Hua Guo, Shi-Chao Wang, Wen-Quan Zhang   +3 more
doaj   +1 more source

Classification of Platelet‐Activating Anti‐Platelet Factor 4 Disorders

International Journal of Laboratory Hematology, EarlyView.
ABSTRACT Introduction The prototypic anti‐platelet factor 4 (PF4) disorder—heparin‐induced thrombocytopenia and thrombosis (HITT)—features immunoglobulin G (IgG) class antibodies that activate platelets, monocytes, and neutrophils in a mainly heparin‐dependent fashion via Fcγ receptor‐dependent cellular activation.
Theodore E. Warkentin
wiley   +1 more source

Successful treatment of acute kidney injury secondary to haeme nephropathy in paroxysmal nocturnal haemoglobinuria with alkaline diuresis [PDF]

, 2012
Paroxysmal nocturnal haemoglobinuria (PNH) also known as ‘Marchiafava Micheli syn-drome’ is a rare condition which can lead to both acute and chronic forms of renal failure through renal tubular haemosiderin deposition. A 45-year-old lady with underlying
Das, S., Fadilah, S.A.W., Sakthiswary, R.   +2 more
core  

Diagnosis and treatment of pediatric acquired aplastic anemia (AAA): An initial survey of the North American Pediatric Aplastic Anemia Consortium (NAPAAC) [PDF]

, 2013
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106711/1/pbc24875 ...
Bennett, Carolyn, Bertuch, Alison, Bessler, Monica, Coates, Thomas, Corey, Seth, Dror, Yigal, Huang, James, Lipton, Jeffrey, Olson, Timothy S., Reiss, Ulrike M., Rogers, Zora R., Shimamura, Akiko, Sieff, Colin, Vlachos, Adrianna, Walkovich, Kelly, Wang, Winfred, Williams, David A.   +16 more
core   +1 more source

Renal hemosiderosis in paroxysmal nocturnal hemoglobinuria

Revista de Medicina da UFC, 2022
A previously healthy 38-year-old man presented with history of fever, adynamia and anemia for the last 5 months. Physical examination revealed pallor. Laboratory was marked by a hemoglobin level of 9.2g per deciliter (reference range, 14.0 to 18.0 g per ...
Italo Gustavo Lima Monteiro, Gabriela Studart Galdino, Raimundo Noberto de Lima Neto   +2 more
doaj   +1 more source

Patient‐Reported Oral Symptoms and Their Impact on Well‐Being After Haematopoietic Cell Transplantation

Oral Diseases, EarlyView.
ABSTRACT Objective Oral complications may negatively influence outcomes of haematopoietic cell transplantation (HCT). A comprehensive view of oral symptoms and symptom burden post‐HCT is lacking. This study aimed to determine the prevalence, severity, and temporal relationships of oral symptoms and their impact on well‐being in the early post‐HCT phase.
Kristina Skallsjö, Michael T. Brennan, Bengt Hasséus, Jenny Öhman, Judith E. Raber‐Durlacher, Marie‐Charlotte D. N. J. M. Huysmans, Alexa M. G. A. Laheij, Stephanie J. M. van Leeuwen, Allan J. Hovan, Karin Garming Legert, Scott Isom, David M. Kline, Nicole M. A. Blijlevens, Jan‐Erik Johansson, Inger von Bültzingslöwen   +14 more
wiley   +1 more source

Long-term efficacy and safety of eculizumab in Japanese patients with generalized myasthenia gravis : a subgroup analysis of the REGAIN open-label extension study [PDF]

, 2019
The terminal complement inhibitor eculizumab was shown to improve myasthenia gravis-related symptoms in the 26-week, phase 3, randomized, double-blind, placebo-controlled REGAIN study (NCT01997229).
De Bleecker, Jan, Fujita, KP, Imai, T, Murai, H, O'Brien, F, Okumura, M, Shiraishi, H, Study Group, REGAIN, Suzuki, H, Suzuki, Y, Utsugisawa, K, Uzawa, A, Wang, JJ   +12 more
core   +1 more source

Very severe aplastic anemia in an 80‐year‐old man

Clinical Case Reports, 2021
Although the patient with very severe aplastic anemia might be a fit elderly receiving standard therapy, there are factors which contribute to an adverse outcome such as severity of pancytopenia, absence of minor paroxysmal nocturnal hemoglobinuria clone
Ganesh Kasinathan, Bee Sun Lee, Jameela Sathar   +2 more
doaj   +1 more source

Paroxysmal Nocturnal Hemoglobinuria: Biology and Treatment

Medicina, 2023
Paroxysmal nocturnal hemoglobinuria (PNH) is a nonmalignant clonal hematopoietic disorder characterized by the lack of glycosylphosphatidylinositol-anchored proteins (GPI-APs) as a consequence of somatic mutations in the phosphatidylinositol glycan ...
Carlos Bravo-Perez, Luca Guarnera, Nakisha D. Williams, Valeria Visconte   +3 more
doaj   +1 more source