Results 241 to 250 of about 3,443,356 (396)
Phytochemical Analysis, EarlyView.ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek +3 more
wiley +1 more source
PROTEOMICS, EarlyView.ABSTRACT Triple‐negative breast cancer (TNBC) is an aggressive subtype of breast cancer characterized by high metastatic potential, poor prognosis, and limited effective therapeutic options. In this study, we investigated the molecular mechanisms underlying the anticancer effects of the nucleolin (NCL)‐targeting DNA aptamer AS1411 using label‐free ...
Ha‐Song Bae +6 more
wiley +1 more source
Precision Medical Sciences, EarlyView.Breast cancer subtypes, estrogen receptor‐positive (ER+), HER2‐enriched, and TNBC, are defined by genomic and epigenetic signatures. Multi‐omics profiling, immunotherapy, liquid biopsy, and AI‐driven radiogenomics enable precision medicine. Tools like Oncotype DX and PAM50 support personalized care.
Samina Malik +4 more
wiley +1 more source
PARP inhibitors synergize with abiraterone [PDF]
Nature Reviews Clinical Oncology, 2018 openaire +2 more sources
Boron‐10 carriers and their applications in boron neutron capture therapy
Precision Radiation Oncology, EarlyView.Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang +7 more
wiley +1 more source
Phytotherapy Research, EarlyView.EGCG suppresses glioma progression by targeting integrin αvβ3/FAK/ERK signaling and inhibiting MMP‐2/MMP‐9‐mediated ECM degradation, thereby blocking proliferation, migration, invasion, and promoting apoptosis. ABSTRACT Epigallocatechin‐3‐gallate (EGCG), the most abundant and biologically active catechin in green tea, has been widely reported to ...
Rui Sun +7 more
wiley +1 more source
Natural Products as Modulators of ABC Transporters in Breast Cancer
Phytotherapy Research, EarlyView.ABSTRACT Breast cancer remains a significant global health challenge, with high incidence and mortality rates despite advancements in early detection and treatment. Multidrug resistance (MDR), particularly in aggressive subtypes like triple‐negative breast cancer (TNBC), continues to hinder effective therapy.
Yoganishalini Sagadevan +2 more
wiley +1 more source
Challenges in employing overall survival as a primary outcome in ovarian cancer studies: insights from PARP inhibitor trials. [PDF]
Front OncolSiegler Y, Matanes E.
europepmc +1 more source
Small, EarlyView.Indocyanine green (ICG) is widely used for near‐infrared imaging but suffers from poor photostability. Here, an indocyanine green–inspired polymeric NIR chromophore is introduced, exhibiting intrinsically enhanced photostability and biocompatibility.
Su Bin Lee +14 more
wiley +1 more source