Results 41 to 50 of about 24,259 (317)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Identification of Partial Discharge Sources by Feature Extraction from a Signal Conditioning System

Sensors
This paper addresses the critical challenge of detecting, separating, and classifying partial discharges in substations. It proposes two solutions: the first involves developing a signal conditioning system to reduce the sampling requirements for PD ...
Itaiara Felix Carvalho, Edson Guedes da Costa, Luiz Augusto Medeiros Martins Nobrega, Allan David da Costa Silva   +3 more
doaj   +1 more source

Partial discharges measurement by UHF method [PDF]

Zbornik Radova: Elektrotehnički Institut "Nikola Tesla", 2020
The unconventional UHF (Ultra High Frequency) method of measuring partial discharges (PD) is based on measuring electromagnetic waves (EM) in the UHF frequency band (300-3000) MHz, using appropriate antennas.
Malešević Nevena, Žarković Mileta, Ilić Denis, Jovanović Đorđe   +3 more
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Influence of Water Ingress on Surface Discharges Occurring on the Silicone Gel Encapsulated Printed Circuit Boards Developed for Deep-Sea Applications

Energies, 2023
This paper discusses the influence of water ingress on the electrical discharges that arise on the surface of printed circuit boards that are developed for deep sea applications.
Saravanakumar Arumugam, Yvonne Haba, Petrus Jacobus Pieterse, Dirk Uhrlandt, Sascha Kosleck   +4 more
doaj   +1 more source

Classification of EMI discharge sources using time–frequency features and multi-class support vector machine [PDF]

, 2018
This paper introduces the first application of feature extraction and machine learning to Electromagnetic Interference (EMI) signals for discharge sources classification in high voltage power generating plants.
Boreham, Philip, Hughes-Narborough, Michael, Mitiche, Imene, Morison, Gordon, Nesbitt, Alan, Stewart, Brian G.   +5 more
core   +2 more sources

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Study of using three dimensional printer for EDM electrode fabrication [PDF]

, 2011
In this study, Cu-Al2O3 powder was prepared using ball mill and used separately for powder metallurgy (PM) and Three Dimensional Printer (3DP) application to fabricate electrode for electrical discharge machining (EDM).
Hassan, Noor Haslyena
core  

Orbitofrontal epilepsy: Electroclinical analysis of surgical cases and literature review [PDF]

, 2004
Clinical and electrographic data were reviewed on 2 of our patients with orbitofrontal epilepsy who were seizure free at 5-year follow-up, and on 2 similar patients from the literature.
King, Don W., Loring, David W., Sillay, Karl, Smith, Joseph R., Winkler, Peter   +4 more
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu, Qi Wang, Suhui Kuang, Dezhi Cao, Ping Ding, Shaohui Zhang, Haihua Wei, Zhirong Wei, Jinshan Xu, Xinyu Huang, Bing Liu, Shuli Liang   +11 more
wiley   +1 more source