Results 21 to 30 of about 21,137 (209)
Can endocan serve as a molecular “hepatostat” in liver regeneration?
Molecular Medicine, 2023 Background Intriguingly, liver regeneration after injury does not induce uncontrolled growth and the underlying mechanisms of such a “hepatostat” are still not clear. Endocan, a proteoglycan, was implicated in liver regeneration.
Sinan Efe Yazici +5 more
doaj +1 more source
c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis
Hepatology, EarlyView., 2022 In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie +17 more
wiley +1 more source
ADENYL NUCLEOTIDES CONTENT IN LIVER MITOCHONDRIA OF RATS WITH ACETAMINOPHEN INTOXICATION AFTER PARTIAL HEPATECTOMY [PDF]
Biotechnologia ActaThe work aimed to assess the content of adenyl nucleotides (ATP, ADP, AMP) and Atkinson’s adenylate energy charge in the mitochondrial fraction of rat liver with acetaminophen-induced toxic injury following partial hepatectomy.
М.S. Ursatyi +2 more
doaj +1 more source
BMC Surgery, 2023 Background The prognosis for hepatocellular carcinoma (HCC) is complex due to its high level of heterogeneity, even after radical resection. This study was designed to develop and validate a prognostic nomogram for predicting the postoperative prognosis ...
Yang Lu, Shuang Ren, Jianning Jiang
doaj +1 more source
TP53 R249S mutation in hepatic organoids captures the predisposing cancer risk
Hepatology, EarlyView., 2022 The systematic approach in elucidating the gain‐of‐function (GOF) roles of TP53 mutations in early liver carcinogenesis. Unique downstream targets of TP53 L3 mutations were identified from chormatin immunoprecipitation sequencing in HCC cell lines, followed by a series of validation assays to substantiate the exclusive transcriptional regulations ...
Yin Kau Lam +10 more
wiley +1 more source
Accumulation and release of triglycerides by rat liver following partial hepatectomy
Journal of Lipid Research, 1970 Regenerating liver accumulates lipid for about 20 hr following partial hepatectomy. During this time incorporation of intravenously administered palmitate-9,10-3H into βlipoprotein increased.
THOMAS J. DELAHUNTY, DAVID RUBINSTEIN
doaj +1 more source
Effect of nebivolol on liver regeneration in an experimental 70% partial hepatectomy model
Asian Journal of Surgery, 2017 Background: Factors affecting liver regeneration are still relevant. The purpose of this study is to investigate the effect of nebivolol treatment on liver regeneration in rats in which 70% partial hepatectomy was performed.
Fatih Sumer +6 more
doaj +1 more source
LAPAROSCOPIC LIVER RESECTION IN THE GOAT [PDF]
Basrah Journal of Veterinary Research, 2015 The aim of this study is to evaluate application of laparoscopy in veterinary surgery and assess the feasibility safety of laparoscopic hepatectomy using thermal energy to control the bleeding after the partial hepatoctomy in the goats.
Jinan A. bannai +2 more
doaj +1 more source
BMC Genomics, 2023 Surgical resection remains a critical treatment option for many patients with primary and secondary hepatic neoplasms. Extended hepatectomy (eHx) may be required for some patients with large tumors, which may cause liver failure and death.
Zeyuan Li +11 more
doaj +1 more source
Effect of hyperbaric oxygenation on the regeneration of the liver after partial hepatectomy in rats
Brazilian Journal of Medical and Biological Research, 2004 The aim of the present study was to assess the influence of hyperbaric oxygenation (HBO) on rat liver regeneration before and after partial hepatectomy.
T.T. Kurir +11 more
doaj +1 more source