Results 111 to 120 of about 11,624,387 (363)
On a linear system of differential equations
Вестник КазНУ. Серия математика, механика, информатика, 2019 The linear systems of partial differential equations of the first order with the identical main parts is considered. Аpplying the well-known relation between a normal system of ordinary differential equations and a linear system of partial differential
T. М. Aldibekov, M. M. Aldazharova
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Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
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Partial Contraction Analysis of Coupled Fractional Order Systems
Journal of Applied Mathematics, 2018 Contraction theory regards the convergence between two arbitrary system trajectories. In this article we have introduced partial contraction theory as an extension of contraction theory to analyze coupled identical fractional order systems. It can, also,
Ahmad Ruzitalab +2 more
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Holomorphic Gromov’s Partial Order [PDF]
The Journal of Geometric Analysis, 2017 As in [5], we study holomorphic maps of positive degree between compact complex manifolds, and prove that any holomorphic map of degree one from a compact complex manifold to itself is biholomorphic. This conclusion confirms that under a mild restriction the holomorphic Gromov relation ">_" is indeed a partial order.
openaire +3 more sources
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
Computational Wavelet Method for Multidimensional Integro-Partial Differential Equation of Distributed Order [PDF]
, 2022 Y. Jeevan Nagendra Kuma +3 more
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Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
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Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source