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The activated partial thromboplastin time (APTT) [PDF]
, 1992 The term partial thromboplastin is used to distinguish the reagent from that used in the prothrombin time, since the APTT reagent lacks the apoprotein component of the complete tissue thromboplastin. The APTT is the main test for screening for intrinsic clotting defects including haemophilia. It is also used for detection of lupus anticoagulant and for
L. Poller, J. M. Thomson
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Use of the Activated Partial Thromboplastin Time
Annals of Internal Medicine, 1988Excerpt To the Editor:In connection with a recent article (1), I pose a question. Should peridural anesthesia in women with otherwise normal bleeding history be preceded by coagulation tests to pre...
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Routine Use of the Prothrombin and Partial Thromboplastin Times
JAMA: The Journal of the American Medical Association, 1989The prothrombin time (PT) and activated partial thromboplastin time (APTT) tests are often routinely ordered for hospitalized patients. Ordering patterns and clinical indications for the PT and APTT tests on the medical service at a teaching hospital were studied. Eighty-one percent of all patients admitted to the medical service had a PT and APTT test
Stephen Erban, Kinman Jl, Schwartz Js
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Activated Partial Thromboplastin Time and Minor Coagulopathies
American Journal of Clinical Pathology, 1979Five commercially available activated partial thromboplastin time (APTT) test systems were compared with the kaolin partial thromboplastin time (KPTT) method to determine sensitivity in detecting minor coagulation defects. All reagent systems detected severe factor VIII-, IX-, and XI-deficient hemophilia.
William E. Hathaway +3 more
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The Partial Thromboplastin Time and Factor VIII Therapy
American Journal of Clinical Pathology, 1972A large pseudotumor was removed from a hemophiliac patient, necessitating the use of long-term, high-dose therapy with factor VIII concentrate. The patient's activated partial thromboplastin time rarely normalized in spite of high factor VIII assay levels. In addition, other routine tests of coagulation became abnormal.
C. Jack Bark, Marshall J. Orloff
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Heparin and Partial Thromboplastin Time: an International Survey
British Journal of Haematology, 1980Summary.The reliability of routine partial thromboplastin time (PTT) methods in the measurement of the anticoagulant effect of heparin has been assessed in a study involving over 300 hospitals in the U.K. and overseas. Commercial PTT methods were relatively insensitive to heparin, added in vitro, compared with the standardized PTT method tested by the ...
K.F. Yee, J. M. Thomson, L. Poller
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Abnormal activated partial thromboplastin time and malignancy
Scottish Medical Journal, 2011Malignancy often results in clotting abnormalities. The aetiology of haemostasis problems in cancer is complex, and is still not completely understood. We describe a case of a patient with malignant mesothelioma, who was found to have elevated activated partial thromboplastin time, due to lupus anticoagulant.
M Delicata, H Hambley
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Shortened activated partial thromboplastin time: causes and management
Blood Coagulation & Fibrinolysis, 2010Throughout the long history of the hemostasis laboratory, and as an evaluation of the coagulation cascade, the results of the activated partial thromboplastin time (APTT) have primarily been considered as an index of loss-of-function and rarely as an index of gain-of-function.
LIPPI, Giuseppe +4 more
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Extremely Shortened Activated Partial Thromboplastin Times
JAMA: The Journal of the American Medical Association, 1980To the Editor.— The presence of a hypercoagulable state in patients with a shortened activated partial thromboplastin time (APTT) as manifested by the clinical association with an increased incidence of thromboembolic disease has previously been reported by Hume, 1 Gallus et al, 2 Pilgeram, 3 McKenna et al, 4 and McKenna et al.
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Correlation Between Activated Clotting Time and Activated Partial Thromboplastin Times
The Annals of Pharmacotherapy, 2002OBJECTIVE: To evaluate the correlation between clotting time tests and heparin concentration, the correlation between activated clotting time (ACT) and activated partial thromboplastin time (aPTT) results, and to compare the clinical decisions based on ACT results with those based on aPTT results.
Susan J. Westley +6 more
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