Results 51 to 60 of about 441,090 (336)

The phenomenon of fan creativity: the main directions of studies

open access: yesRUDN Journal of Studies in Literature and Journalism, 2020
The article considers the main directions of foreign and domestic studies of fan communities and fan creative production. The article synthesizes theoretical knowledge collected abroad.
Leila O. Algavi, Alina V. Kharchenko
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

“No Geek Girls”: Boundary-Work and Gendered Identity in the Israeli Geek Community

open access: yesInternational Journal of Communication, 2022
Boundary-work theory describes the discursive efforts of groups to limit access to membership and collective symbolic capital. In this article, we explore the gendered nature of boundary-work within an online community of Geeks—a subcultural identity ...
Hadas Gur-Ze'ev, Neta Kligler-Vilenchik
doaj  

Political Science Perceptions of Post-Soviet Civic Participation: Reconciliation Steps or an Attempt at Imitation?

open access: yesJournal of Political Science: Bulletin of Yerevan University, 2022
In the study of the perceptions of post-Soviet political participation, the article substantiated the study of the issue of political participation, the theoretical bases of the analysis of political participation in the stage of democratic ...
Arnak Sargsyan
doaj   +1 more source

Rethinking the participatory web: A history of HotWired’s “new publishing paradigm,” 1994–1997 [PDF]

open access: yes, 2014
This article critically interrogates key assumptions in popular web discourse by revisiting an early example of web ‘participation.’ Against the claim that Web 2.0 technologies ushered in a new paradigm of participatory media, I turn to the history of ...
Michael Stevenson
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Unveiling the War and Constructing Identities: Exploring Memes in Ukrainian and Russian Social Media during the Russian Invasion of Ukraine

open access: yesCzech Journal of International Relations
The article examines the generation and deployment of visual narratives in Ukrainian and Russian digital participatory cultures, with a specific focus on internet memes in the context of the Russian invasion of Ukraine. It analyzes the form, content, and
ALINA MOZOLEVSKA
doaj   +1 more source

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