Results 51 to 60 of about 441,090 (336)
The phenomenon of fan creativity: the main directions of studies
The article considers the main directions of foreign and domestic studies of fan communities and fan creative production. The article synthesizes theoretical knowledge collected abroad.
Leila O. Algavi, Alina V. Kharchenko
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
“No Geek Girls”: Boundary-Work and Gendered Identity in the Israeli Geek Community
Boundary-work theory describes the discursive efforts of groups to limit access to membership and collective symbolic capital. In this article, we explore the gendered nature of boundary-work within an online community of Geeks—a subcultural identity ...
Hadas Gur-Ze'ev, Neta Kligler-Vilenchik
doaj
In the study of the perceptions of post-Soviet political participation, the article substantiated the study of the issue of political participation, the theoretical bases of the analysis of political participation in the stage of democratic ...
Arnak Sargsyan
doaj +1 more source
Rethinking the participatory web: A history of HotWired’s “new publishing paradigm,” 1994–1997 [PDF]
This article critically interrogates key assumptions in popular web discourse by revisiting an early example of web ‘participation.’ Against the claim that Web 2.0 technologies ushered in a new paradigm of participatory media, I turn to the history of ...
Michael Stevenson
core +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source
The article examines the generation and deployment of visual narratives in Ukrainian and Russian digital participatory cultures, with a specific focus on internet memes in the context of the Russian invasion of Ukraine. It analyzes the form, content, and
ALINA MOZOLEVSKA
doaj +1 more source
“No Apple iPhone? You must be Canadian”: mobile technologies, participatory culture, and rhetorical transformation [PDF]
Isabel Pedersen
openalex +1 more source

