Results 81 to 90 of about 441,738 (307)
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
What's Going on in Community Media [PDF]
, 2007 What's Going On in Community Media shines a spotlight on media practices that increase citizen participation in media production, governance, and policy.
Fred Johnson, Karen Menichelli
core
Perceptions and determinants of partnership trust in the context of Community-Based Participatory Research [PDF]
, 2020 Trust is difficult to conceptualize and define because of its diverse applications in different disciplines. Historic mistrust between vulnerable communities and researchers based on past adverse experiences can negatively affect the ability to ...
Moore de Peralta, Arelis +2 more
core +2 more sources
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Getting In On the Act: How Arts Groups are Creating Opportunities for Active Participation [PDF]
, 2011 Arts participation is being redefined as people increasingly choose to engage with art in new, more active and expressive ways. This movement carries profound implications, and fresh opportunities, for the nonprofit arts sector.We are in the midst of a ...
Alan S. Brown +2 more
core
Hos in the garden: staging and resisting neoliberal creativity [PDF]
, 2016 This article takes up the challenge of extending and enhancing the literature on arts interventions and creative city policies by considering the role of feminist and queer artistic praxis in contemporary urban politics.
McLean, Heather
core +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Journal of Social Work Education and Practice, 2023 The new socio-political and economic context sponsored by globalization, the revaluation of particular political interests, linked more with specific problems than with the great left and right ideologies of traditional political organizations and the ...
Patricia Castro
doaj
A Study of DNN-Based Media Literacy and Distance Education Management System in the Context of Participatory Culture. [PDF]
Comput Intell Neurosci, 2022 Xu R, Wang C, Hsu Y.
europepmc +1 more source
COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source