Results 121 to 130 of about 279,255 (349)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Deliberative Visioning: A Critical View Observations From a Scenario Workshop for Water Management in a Greek Island [PDF]
There is a growing policy interest in participatory processes that combine deliberation with futures visioning. The EU Water Framework Directive, with its mandate for participatory long-term river basin plans, contributes to this “futures turn†in ...
Alexandra Mexa +4 more
core
Integration of multi-scale stakes in governance by applying companion modelling to land use foresight [PDF]
, 2009 Decentralization of land use governance creates new challenges for participatory approaches, including the involvement of highly diverse participants and the search for coherence among multiple regulations.
Antona, Martine +3 more
core
The potential role of socio-hydrological models for participatory water governance in Burkina Faso [PDF]
, 2020 Halting and reversing water quality degradation is a major global concern. The variety of needs and priorities placed on water resources make the issue of water pollution multifaceted and complex.
Barendrecht, Marlies +2 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Exploring the interplay between urban governance and smart services codesign [PDF]
Interaction Design and Architecture(s), 2014 The large spreading of e-democracy and e-participatory tools and environments showed, and is still showing, that technologies offer new direction for dealing with the challenge of scaling the deliberative democracy perspective up to the urban governance ...
Grazia Concilio +2 more
doaj
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Empowerment or legitimation? The Angolan Conselhos de Auscultação e Concertação Social
Revista Iberoamericana de Estudios de Desarrollo, 2012 The Conselhos de Auscultação e Concertação Social (CACS) of Angola are spaces of participatory governance, where local authorities have to consult and be accountable to society.
Hueso González, Andrés
doaj
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
BuildingsThe Work-Unit Compound (WUC) is a common neighborhood type that became prevalent during China’s socialist era, typically offering communal spaces that serve as vital spatial carriers for communal life. Following the shift in public housing provision from
Yueli Xu, Han Wang, Bing Xia
doaj +1 more source